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Dergiler / Hacettepe Journal of Biology and Chemistry / 2026 / Volume: 43 Issue: 3

Bazı Yenebilir Mantar Ekstrelerinin İnsan Karbonik Anhidraz İzozimleri Üzerine Etkilerinin İncelenmesi

Investigation of The Effects of Some Edible Mushroom Extracts on Human Carbonic Anhydrase Isozymes

Hülya Karaçam(Dumlupınar University, Faculty of Arts and Sciences, Department of Biochemistry, Kütahya, Turkey.)
Ekrem Tunca(Dumlupınar University, Faculty of Arts and Sciences, Department of Biochemistry, Kütahya, Turkey.)
Yasemin Kaygısız(Dumlupınar University, Faculty of Arts and Sciences, Department of Biochemistry, Kütahya, Turkey.)
Gözde İmdat(Dumlupınar University, Faculty of Arts and Sciences, Department of Biochemistry, Kütahya, Turkey.)
Metin Bülbül(Dumlupınar University, Faculty of Arts and Sciences, Department of Biochemistry, Kütahya, Turkey.)
Sayfa
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Yayın Tarihi
2015-09-01
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Ancak diğer özütler hCA I ve II nin esteraz aktiviteleri üzerinde aktivatör etki göstermişlerdir

📌 3 Maddede Bu Makale

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Amaç & Hipotez:B u çalışmada, dört yenebilir mantar türünün Lentinula edodes, Lactarius deliciosus, Lactarius deterrimus, Terfezia boudieri insan karbonik anhidraz izoenzimleri hCA I ve hCA II üzerine etkileri in vitro olarak incelenmiştir. hCA I ve II izoenzimleri Sepharose®4B-L-tirozin-p-aminobenzen sülfonamit afinite kromatografisi kullanılarak eritrositlerden saflaştırıldı.
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Temel Bulgular & Veri:Daha sonra mantar özütlerinin hCA I ve II izoenzimlerinin hidrataz ve esteraz aktivitelerinin üzerine etkileri ölçüldü.
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Sonuç & Katkı:Ancak diğer özütler hCA I ve II nin esteraz aktiviteleri üzerinde aktivatör etki göstermişlerdir
🔬Tür:Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Carbonic anhydrase · hydratase activity · esterase activity

Özet

B u çalışmada, dört yenebilir mantar türünün Lentinula edodes, Lactarius deliciosus, Lactarius deterrimus, Terfezia boudieri insan karbonik anhidraz izoenzimleri hCA I ve hCA II üzerine etkileri in vitro olarak incelenmiştir. hCA I ve II izoenzimleri Sepharose®4B-L-tirozin-p-aminobenzen sülfonamit afinite kromatografisi kullanılarak eritrositlerden saflaştırıldı. Daha sonra mantar özütlerinin hCA I ve II izoenzimlerinin hidrataz ve esteraz aktivitelerinin üzerine etkileri ölçüldü. L. edodes hCA I ve II nin esteraz aktiviteleri üzerinde inhibitor etki göstermiştir. Ancak diğer özütler hCA I ve II nin esteraz aktiviteleri üzerinde aktivatör etki göstermişlerdir

Abstract

In this study the effects of four edible mushroom species Lentinula edodes, Lactarius deliciosus, Lactarius deterrimus, Terfezia boudieri on human carbonic anhydrase isozymes hCA I and hCA II were investiga- ted as in vitro. hCA I and II isozymes were purified from erythrocytes by using Sepharose®4B-L-tyrosine-p- aminobenzene sulfonamide affinity chromatography. Later the effects of the mushroom extracts on the hydra- tase and esterase activities of hCA I and II were measured. L. edodes showed inhibitory effect on the esterase activities of hCA I and II. However, other extracts showed activator effects on the esterase activities of hCA I and II.

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Bu Makaleye Atıf Yap

Karaçam, H., Tunca, E., Kaygısız, Y., İmdat, G., Bülbül, M. (2015). Bazı Yenebilir Mantar Ekstrelerinin İnsan Karbonik Anhidraz İzozimleri Üzerine Etkilerinin İncelenmesi. Hacettepe Journal of Biology and Chemistry, Volume: 43 Issue: 3. https://ajindex.com/articles/1270842

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