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Dergiler / Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi / 2026 / Cilt: 6 Özel Sayı

Bakır(II) Komplekslerinin Glutatyon Redüktaz İnhibitor Çalışması

Studies of Glutathione Reductase Inhibitors Activity of Copper(II) Complexes

Turgay Tunç(AHİ EVRAN ÜNİVERSİTESİ)0000-0002-2431-8027
Sayfa
117–122
Yayın Tarihi
2019-09-30
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

En iyi inhibitör etkisinin kompleks 3'e ait olduğu belirlenmiştir.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:(S)-(+)-fenilglisinol, (1S, 2R) -2-amino- 1,2-difeniletanol’ in ve (R)-(+)-2-amino-1,1,3-trifenilpropanol bazlı kiral Schiff bazlarının bakır (II) kompleksi sentezlendi.
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Temel Bulgular & Veri:Bu bileşiklerin glutatyon redüktaz enzimi üzerindeki etkileri incelendi.
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Sonuç & Katkı:En iyi inhibitör etkisinin kompleks 3'e ait olduğu belirlenmiştir.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Schiff baz · bakır (II) kompleksleri · Glutatyon Redüktaz

Özet

(S)-(+)-fenilglisinol, (1S, 2R) -2-amino- 1,2-difeniletanol’ in ve (R)-(+)-2-amino-1,1,3-trifenilpropanol bazlı kiral Schiff bazlarının bakır (II) kompleksi sentezlendi. Bu bileşiklerin glutatyon redüktaz enzimi üzerindeki etkileri incelendi. En iyi inhibitör etkisinin kompleks 3'e ait olduğu belirlenmiştir.

Abstract

(S)-(+) - phenylglycinol, (1S, 2R)-2-amino-1, 2-diphenylethanol and (R)-(+)-2-amino-1, 1, 3-triphenylpropanol based chiral copper (II) complex of Schiff bases were synthesized. The effects of these compounds on glutathione reductase enzyme were investigated. The best inhibitory effect was found to belong to complex 3.

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Bu Makaleye Atıf Yap

Tunç, T. (2019). Bakır(II) Komplekslerinin Glutatyon Redüktaz İnhibitor Çalışması. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, Cilt: 6 Özel Sayı, 117–122. https://doi.org/10.35193/bseufbd.577450

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Kaynakça (23)

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