Dergiler / Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi / 2026 / Volume: 31 Issue: 1

Geçmişten Günümüze Genetik ve Kromozom Mühendisliği Çalışmalarının Sürdürülebilir Tarım ve Bitki Islahına Katkısı

Contribution of Genetic and Chromosome Engineering Studies from Past to Present to Sustainable Agriculture and Plant Breeding

Sevim Kara Öztürk(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TARIM BİLİMLERİ VE TEKNOLOJİLERİ FAKÜLTESİ, TARIMSAL GENETİK MÜHENDİSLİĞİ BÖLÜMÜ)0000-0001-7522-0575
Bilge Yıldırım(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TARIM BİLİMLERİ VE TEKNOLOJİLERİ FAKÜLTESİ, TARIMSAL GENETİK MÜHENDİSLİĞİ BÖLÜMÜ)0000-0001-6593-4312
Hümeyra Yıldız(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TARIM BİLİMLERİ VE TEKNOLOJİLERİ FAKÜLTESİ, TARIMSAL GENETİK MÜHENDİSLİĞİ BÖLÜMÜ)0000-0002-7791-6100
Ahmet L. Tek(NİĞDE ÜNİVERSİTESİ, TARIM BİLİMLERİ VE TEKNOLOJİLERİ FAKÜLTESİ, TARIMSAL GENETİK MÜHENDİSLİĞİ BÖLÜMÜ, TARIMSAL BİYOİNFORMATİK ANABİLİM DALI)0000-0002-3292-5142
Sayfa
—
Yayın Tarihi
2021-03-30
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Tüm bunlara ek olarak, bu derleme makalesinde bir araya getirilen güncel ve hızlı gelişen disiplinler arası tematik çalışmalar ve aynı zamanda tarım, ıslah ve genetik disiplinlerinden sentezlenen perspektiflerin, bu alanlarda çalışan araştırmacılara yönlendirici bir tartışma platformu sunması hedeflenmiştir.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:2050 yılında nüfusun 9.2 milyara ulaşacağı ve dünya genelinde eşit ve insani temel ihtiyaçlara olan taleplerin karşılanması gerektiği öngörülmektedir.
📊
Temel Bulgular & Veri:Bununla birlikte birim alandan daha yüksek verim alınmasını sağlayan yeni teknoloji ve yöntemlerin geliştirilip bitki ıslah programlarına entegre edilmesi gerekmektedir.
💡
Sonuç & Katkı:Tüm bunlara ek olarak, bu derleme makalesinde bir araya getirilen güncel ve hızlı gelişen disiplinler arası tematik çalışmalar ve aynı zamanda tarım, ıslah ve genetik disiplinlerinden sentezlenen perspektiflerin, bu alanlarda çalışan araştırmacılara yönlendirici bir tartışma platformu sunması hedeflenmiştir.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:2050 Verileri
⚙️Değişkenler:Biotechnology · Chromosome engineering · Genetic engineering

Özet

2050 yılında nüfusun 9.2 milyara ulaşacağı ve dünya genelinde eşit ve insani temel ihtiyaçlara olan taleplerin karşılanması gerektiği öngörülmektedir. Günümüze kadar, tarımsal üretimin arttırılmasına yönelik çeşitli çalışmalar gerçekleştirilmiştir. Bununla birlikte birim alandan daha yüksek verim alınmasını sağlayan yeni teknoloji ve yöntemlerin geliştirilip bitki ıslah programlarına entegre edilmesi gerekmektedir. Bu entegrasyon sayesinde hem sürdürülebilir tarım anlayışına uyumsuz aşırı girdi ve mekanizasyon kullanımı azaltılabilecek hem de bitki biyolojisi, evrimi, genom yapısı anlaşılarak tarımda verimlilik arttırılabilecektir. Ayrıca genetik çeşitlilikten yararlanılması, model bitkilerden sağlanan verilerin bitki ıslah programlarına adapte edilmesi, yetim bitkilerin genetik kaynak potansiyelinin kullanılmasına yönelik çalışmalar yeni genotiplerin eldesine katkı sağlayacaktır. Bugüne kadar gen transformasyonu, DNA dizilemesi, genom haritalaması ve genom düzenleme gibi modern teknolojiler bitkilerde genom yapısının anlaşılmasında etkin rol oynamıştır. FISH, GISH, telomer aracılığıyla kromozom kesimi, minikromozomlar, organizmalar arası sintenik kromozomal lokuslarının saptanması, tekrarlayan DNA elementlerinin keşfi ve yapısal CENH3 proteininin kullanımı gibi çok sayıda kromozom mühendisliği yöntemleri de tarımsal gelişmede itici güç oluşturacaktır. Temel bilimlerdeki ilerlemelerden faydalanan tarımsal araştırmalar uzun vadede istenilen amaca ulaşmayı destekleyecek ve gelecekte kromozom mühendisliği yöntemleri özelinde tarımsal üretimin artırılmasına katkı sağlayacaktır. Tüm bunlara ek olarak, bu derleme makalesinde bir araya getirilen güncel ve hızlı gelişen disiplinler arası tematik çalışmalar ve aynı zamanda tarım, ıslah ve genetik disiplinlerinden sentezlenen perspektiflerin, bu alanlarda çalışan araştırmacılara yönlendirici bir tartışma platformu sunması hedeflenmiştir.

Abstract

It is predicted that by 2050 the population will reach 9.2 billion and the demands for equal and basic needs must be met worldwide. Until today, various studies have been carried out to increase agricultural production. However, new technologies and methods that ensure higher yields per unit area should be developed and integrated into plant breeding programs. While contradictory practices to sustainable agriculture should still be reduced, productivity in agriculture can be increased by understanding plant biology, evolution, and genome structure. In addition, efficient use of genetic diversity, adaptation of knowledge from model plants to breeding programs, and the genetic resource potential of orphan plants will contribute to the development of new genotypes. So far, modern technologies such as gene transformation, DNA sequencing, genome mapping and genome editing have played an active role in understanding the genome structure in plants. Numerous chromosome engineering methods such as FISH, GISH, chromosome truncation via telomeres, mini chromosomes, detection of syntenic chromosomal loci between organisms, discovery of repetitive DNA elements and the use of structural CENH3 protein will also be a driving force in agricultural development. Agricultural research, benefiting from the advances in basic sciences, will support achieving the desired goal in the long term. Potentially, chromosome engineering methods contribute to the increase of agricultural production in the future. In this review article, we aim to create a discussion platform for researchers by providing unique perspectives synthesized from agriculture, breeding and genetics and bringing together the current and rapidly developing interdisciplinary thematic studies.

🔖

Bu Makaleye Atıf Yap

Öztürk, S. K., Yıldırım, B., Yıldız, H., Tek, A. L. (2021). Geçmişten Günümüze Genetik ve Kromozom Mühendisliği Çalışmalarının Sürdürülebilir Tarım ve Bitki Islahına Katkısı. Yüzüncü Yıl Üniversitesi Tarım Bilimleri Dergisi, Volume: 31 Issue: 1. https://doi.org/10.29133/yyutbd.787094

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (78)

  1. Acquaah, G. (2009). Principles of Plant Genetics and Breeding. John Wiley & Sons. 1-22.
  2. Agarwal, M., Shrivastava, N., & Padh, H. (2008). Advances in molecular marker techniques and their applications in plant sciences. Plant Cell Reports, 27(4), 617-631. https://doi.org/10.1007/s00299-008-0507-z
  3. Aguilar-Rivera, N., Michel-Cuello, C., & Cárdenas-González, J. F. (2019). Green Revolution and Sustainable Development. In W. Leal Filho (Ed.), Encyclopedia of Sustainability in Higher Education (pp. 833-850). Springer International Publishing.
  4. Armstead, I., Huang, L., Ravagnani, A., Robson, P., & Ougham, H. (2009). Bioinformatics in the orphan crops. Briefings in Bioinformatics, 10(6), 645-653. https://doi.org/10.1093/bib/bbp036
  5. Barampuram, S., & Zhang, Z. J. (2011). Recent advances in plant transformation. Methods in Molecular Biology (Clifton, N.J.), 701, 1-35. https://doi.org/10.1007/978-1-61737-957-4_1
  6. Bennetzen, J. L., & Chen, M. (2008). Grass Genomic Synteny Illuminates Plant Genome Function and Evolution. Rice, 1(2), 109-118. https://doi.org/10.1007/s12284-008-9015-6
  7. Birchler, J. A., Yu, W., & Han, F. (2008). Plant engineered minichromosomes and artificial chromosome platforms. Cytogenetic and Genome Research, 120(3-4), 228-232. https://doi.org/10.1159/000121071
  8. Biscotti, M. A., Olmo, E., & Heslop-Harrison, J. S. P. (2015). Repetitive DNA in eukaryotic genomes. Chromosome Research: An International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology, 23(3), 415-420. https://doi.org/10.1007/s10577-015-9499-z
  9. Bonierbale, M. W., Plaisted, R. L., & Tanksley, S. D. (1988). RFLP Maps Based on a Common Set of Clones Reveal Modes of Chromosomal Evolution in Potato and Tomato. Genetics, 120(4), 1095-1103.
  10. Brodt, S., Six, J., Feenstra, G., Ingels, C. & Campbell, D. (2011) Sustainable Agriculture. Nature Education Knowledge 3(10):1. https://www.nature.com/scitable/knowledge/library/sustainable-agriculture-23562787/. Erişim tarihi: 12.05.2020.
  11. Cerit, İ., Cömertpay, G., Oyucu, R., Çakir, B., Hatipoğlu, R., & Özkan, H. (2016). Melez Mısır Islahında In-Vivo Katlanmış Haploid Tekniğinde Kullanılan Farklı Inducer Genotiplerin Haploid İndirgeme Oranların Belirlenmesi. Tarla Bitkileri Merkez Araştırma Enstitüsü Dergisi, 25(1), 52-57. https://doi.org/10.21566/tarbitderg.280162
  12. Chang, C., Bowman, J. L., & Meyerowitz, E. M. (2016). Field Guide to Plant Model Systems. Cell, 167(2), 325-339. https://doi.org/10.1016/j.cell.2016.08.031
  13. Charlesworth, B., Sniegowski, P., & Stephan, W. (1994). The evolutionary dynamics of repetitive DNA in eukaryotes. Nature, 371(6494), 215-220. https://doi.org/10.1038/371215a0
  14. Che, P., Anand, A., Wu, E., Sander, J. D., Simon, M. K., Zhu, W., Sigmund, A. L., Zastrow-Hayes, G., Miller, M., Liu, D., Lawit, S. J., Zhao, Z.-Y., Albertsen, M. C., & Jones, T. J. (2018). Developing a flexible, high-efficiency Agrobacterium-mediated sorghum transformation system with broad application. Plant Biotechnology Journal, 16(7), 1388-1395. https://doi.org/10.1111/pbi.12879
  15. Clark, W. C. (2007). Sustainability Science: A room of its own. Proceedings of the National Academy of Sciences, 104(6), 1737-1738. https://doi.org/10.1073/pnas.0611291104
  16. Cody, J. P., Swyers, N. C., McCaw, M. E., Graham, N. D., Zhao, C., & Birchler, J. A. (2015). Minichromosomes: Vectors for Crop Improvement. Agronomy, 5(3), 309-321. https://doi.org/10.3390/agronomy5030309
  17. Cook, D. R., & Varshney, R. K. (2010). From genome studies to agricultural biotechnology: Closing the gap between basic plant science and applied agriculture. Current Opinion in Plant Biology, 13(2), 115-118. https://doi.org/10.1016/j.pbi.2010.03.003
  18. Dhar, M. K., Kaul, S., & Kour, J. (2011). Towards the development of better crops by genetic transformation using engineered plant chromosomes. Plant Cell Reports, 30(5), 799-806. https://doi.org/10.1007/s00299-011-1001-6
  19. Eid, J., Fehr, A., Gray, J., Luong, K., Lyle, J., Otto, G., Peluso, P., Rank, D., Baybayan, P., Bettman, B., Bibillo, A., Bjornson, K., Chaudhuri, B., Christians, F., Cicero, R., Clark, S., Dalal, R., deWinter, A., Dixon, J., … Turner, S. (2009). Real-Time DNA Sequencing from Single Polymerase Molecules. Science, 323(5910), 133-138. https://doi.org/10.1126/science.1162986
  20. Falistocco, E. (2020). Insight into the Chromosome Structure of the Cultivated Tetraploid Alfalfa (Medicago sativa subsp. Sativa L.) by a Combined Use of GISH and FISH Techniques. Plants, 9(4), 542. https://doi.org/10.3390/plants9040542
  21. Faris, J., Sirikhachornkit, A., Haselkorn, R., Gill, B., & Gornicki, P. (2001). Chromosome Mapping and Phylogenetic Analysis of the Cytosolic Acetyl-CoA Carboxylase Loci in Wheat. Molecular Biology and Evolution, 18(9), 1720-1733. https://doi.org/10.1093/oxfordjournals.molbev.a003960
  22. FAO (2020). Food and Agriculture organization. http://www.fao.org/sustainability/en/. Erişim 15.04.2020.
  23. Fears, R. (2007). Genomıcs and genetıc resources for food and agrıculture. Commıssıon on genetıc resources for food and agrıculture. http://www.fao.org/3/a-k0174e.pdf. Erişim 12.06.2020.
  24. Fleury, D., Baumann, U., & Langridge, P. (2012). Plant genome sequencing: Models for developing synteny maps and association mapping. In A. Altman & P. M. Hasegawa (Ed.), Plant Biotechnology and Agriculture (pp. 83-97). Academic Press.
  25. Galasso, I., Harrison, G. E., Pignone, D., Brandes, A., & Heslop-harrison, J. S. (1997). The Distribution and Organization of Ty1-copia-like Retrotransposable Elements in the Genome of Vigna unguiculata (L.) Walp. (Cowpea) and its Relatives. Annals of Botany, 80(3), 327-333. https://doi.org/10.1006/anbo.1997.0443.
  26. Gill, B. S., Friebe, B., & Endo, T. R. (1991). Standard karyotype and nomenclature system for description of chromosome bands and structural aberrations in wheat (Triticum aestivum). Genome, 34(5), 830-839. https://doi.org/10.1139/g91-128
  27. Govindaraj, M., Vetriventhan, M., & Srinivasan, M. (2015). Importance of genetic diversity assessment in crop plants and its recent advances: An overview of its analytical perspectives. Genetics Research International, 2015, 431487. https://doi.org/10.1155/2015/431487
  28. Gross, B. L., Kellogg, E. A., & Miller, A. J. (2014). Speaking of food: Connecting basic and applied plant science. American Journal of Botany, 101(10), 1597-1600. https://doi.org/10.3732/ajb.1400409
  29. Harris, T. D., Buzby, P. R., Babcock, H., Beer, E., Bowers, J., Braslavsky, I., Causey, M., Colonell, J., Dimeo, J., Efcavitch, J. W., Giladi, E., Gill, J., Healy, J., Jarosz, M., Lapen, D., Moulton, K., Quake, S. R., Steinmann, K., Thayer, E., … Xie, Z. (2008). Single-molecule DNA sequencing of a viral genome. Science (New York, N.Y.), 320(5872), 106-109. https://doi.org/10.1126/science.1150427
  30. Henikoff, S., Ahmad, K., Platero, J. S., & van Steensel, B. (2000). Heterochromatic deposition of centromeric histone H3-like proteins. Proceedings of the National Academy of Sciences of the United States of America, 97(2), 716-721. https://doi.org/10.1073/pnas.97.2.716
  31. Heslop‐Harrison, J. (Pat), & Schmidt, T. (2012). Plant nuclear genome composition. In ELS. American Cancer Society. https://doi.org/10.1002/9780470015902.a0002014.pub2
  32. Hidalgo, O., Pellicer, J., Christenhusz, M., Schneider, H., Leitch, A. R., & Leitch, I. J. (2017). Is there an upper limit to genome size? Trends in Plant Science, 22(7), 567-573. https://doi.org/10.1016/j.tplants.2017.04.005
  33. Houben, A., & Schubert, I. (2003). DNA and proteins of plant centromeres. Current Opinion in Plant Biology, 6(6), 554-560. https://doi.org/10.1016/j.pbi.2003.09.007
  34. Houben, A., Nasuda, S., & Endo, T. R. (2011). Plant B chromosomes. Methods in Molecular Biology (Clifton, N.J.), 701, 97-111. https://doi.org/10.1007/978-1-61737-957-4_5
  35. Hribová, E., Neumann, P., Matsumoto, T., Roux, N., Macas, J., & Dolezel, J. (2010). Repetitive part of the banana (Musa acuminata) genome investigated by low-depth 454 sequencing. BMC Plant Biology, 10, 204. https://doi.org/10.1186/1471-2229-10-204
  36. Kato, A., Vega, J. M., Han, F., Lamb, J. C., & Birchler, J. A. (2005). Advances in plant chromosome identification and cytogenetic techniques. Current Opinion in Plant Biology, 8(2), 148-154. https://doi.org/10.1016/j.pbi.2005.01.014
  37. Ku, H.-M., Vision, T., Liu, J., & Tanksley, S. D. (2000). Comparing sequenced segments of the tomato and Arabidopsis genomes: Large-scale duplication followed by selective gene loss creates a network of synteny. Proceedings of the National Academy of Sciences, 97(16), 9121-9126. https://doi.org/10.1073/pnas.160271297
  38. Kuppu, S., Ron, M., Marimuthu, M. P. A., Li, G., Huddleson, A., Siddeek, M. H., Terry, J., Buchner, R., Shabek, N., Comai, L., & Britt, A. B. (2020). A variety of changes, including CRISPR/Cas9-mediated deletions, in CENH3 lead to haploid induction on outcrossing. Plant Biotechnology Journal. https://doi.org/10.1111/pbi.13365
  39. Lermontova, I., & Schubert, I. (2013). CENH3 for Establishing and Maintaining Centromeres. In J. Jiang & J. A. Birchler (Eds). Plant Centromere Biology (pp. 67-82). John Wiley & Sons, Ltd.
  40. Lusser, M., Parisi, C., Plan, D., & Rodríguez-Cerezo, E. (2012). Deployment of new biotechnologies in plant breeding. Nature Biotechnology, 30(3), 231-239. https://doi.org/10.1038/nbt.2142
  41. Mabhaudhi, T., Chimonyo, V. G. P., Hlahla, S., Massawe, F., Mayes, S., Nhamo, L., & Modi, A. T. (2019). Prospects of orphan crops in climate change. Planta, 250(3), 695-708. https://doi.org/10.1007/s00425-019-03129-y
  42. Mandáková, T., & Lysak, M. A. (2008). Chromosomal Phylogeny and Karyotype Evolution in x=7 Crucifer Species (Brassicaceae). The Plant Cell, 20(10), 2559-2570. https://doi.org/10.1105/tpc.108.062166
  43. McCouch, S. R. (2001). Genomics and Synteny. Plant Physiology, 125(1), 152-155. https://doi.org/10.1104/pp.125.1.152
  44. Mehrotra, S., & Goyal, V. (2014). Repetitive sequences in plant nuclear DNA: Types, distribution, evolution and function. Genomics, Proteomics & Bioinformatics, 12(4), 164-171. https://doi.org/10.1016/j.gpb.2014.07.003
  45. Michael, T. P., & VanBuren, R. (2020). Building near-complete plant genomes. Current Opinion in Plant Biology, 54, 26-33. https://doi.org/10.1016/j.pbi.2019.12.009
  46. Mondini, L., Noorani, A., & Pagnotta, M. A. (2009). Assessing Plant Genetic Diversity by Molecular Tools. Diversity, 1(1), 19-35. https://doi.org/10.3390/d1010019
  47. Moose, S. P., & Mumm, R. H. (2008). Molecular Plant Breeding as the Foundation for 21st Century Crop Improvement. Plant Physiology, 147(3), 969-977. https://doi.org/10.1104/pp.108.118232
  48. Muiruri, K. S., Britt, A., Amugune, N. O., Nguu, E. K., Chan, S., & Tripathi, L. (2017). Expressed centromere specific histone 3 (CENH3) variants in cultivated triploid and wild diploid bananas (Musa spp.). Frontiers in Plant Science, 8, 1034. https://doi.org/10.3389/fpls.2017.01034
  49. Murata, M. (2014). Minichromosomes and artificial chromosomes in Arabidopsis. Chromosome Research, 22(2), 167-178. https://doi.org/10.1007/s10577-014-9421-0
  50. Nagaki, K., Cheng, Z., Ouyang, S., Talbert, P. B., Kim, M., Jones, K. M., Henikoff, S., Buell, C. R., & Jiang, J. (2004). Sequencing of a rice centromere uncovers active genes. Nature Genetics, 36(2), 138-145. https://doi.org/10.1038/ng1289
  51. Naylor, R. L., Falcon, W. P., Goodman, R. M., Jahn, M. M., Sengooba, T., Tefera, H., & Nelson, R. J. (2004). Biotechnology in the developing world: A case for increased investments in orphan crops. Food Policy, 29(1), 15-44. https://doi.org/10.1016/j.foodpol.2004.01.002
  52. O’Neill, C. M., & Bancroft, I. (2000). Comparative physical mapping of segments of the genome of Brassica oleracea var. Alboglabra that are homoeologous to sequenced regions of chromosomes 4 and 5 of Arabidopsis thaliana. The Plant Journal: For Cell and Molecular Biology, 23(2), 233-243. https://doi.org/10.1046/j.1365-313x.2000.00781.x
  53. Paoletti, M. G., Gomiero, T., & Pimentel, D. (2011). Introduction to the Special Issue: Towards A More Sustainable Agriculture. Critical Reviews in Plant Sciences, 30(1-2), 2-5. https://doi.org/10.1080/07352689.2011.553148
  54. Palmer, D. K., O’Day, K., Trong, H. L., Charbonneau, H., & Margolis, R. L. (1991). Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone. Proceedings of the National Academy of Sciences of the United States of America, 88(9), 3734-3738. https://doi.org/10.1073/pnas.88.9.3734
  55. Pretty, J. (2008). Agricultural sustainability: Concepts, principles and evidence. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1491), 447-465. https://doi.org/10.1098/rstb.2007.2163
  56. Ramanatha Rao, V., & Hodgkin, T. (2002). Genetic diversity and conservation and utilization of plant genetic resources. Plant Cell, Tissue and Organ Culture, 68(1), 1-19. https://doi.org/10.1023/A:1013359015812
  57. Ravi, M., & Chan, S. W. L. (2010). Haploid plants produced by centromere-mediated genome elimination. Nature, 464(7288), 615-618. https://doi.org/10.1038/nature08842
  58. Ribaut, J.-M., & Ragot, M. (2019). Modernising breeding for orphan crops: Tools, methodologies, and beyond. Planta, 250(3), 971-977. https://doi.org/10.1007/s00425-019-03200-8
  59. Ronald, P. (2011). Plant Genetics, Sustainable Agriculture and Global Food Security. Genetics, 188(1), 11-20. https://doi.org/10.1534/genetics.111.128553
  60. Ronald, P. C. (2014). Lab to Farm: Applying Research on Plant Genetics and Genomics to Crop Improvement. PLoS Biology, 12(6), e1001878. https://doi.org/10.1371/journal.pbio.1001878
  61. Sanei, M., Pickering, R., Kumke, K., Nasuda, S., & Houben, A. (2011). Loss of centromeric histone H3 (CENH3) from centromeres precedes uniparental chromosome elimination in interspecific barley hybrids. Proceedings of the National Academy of Sciences, 108(33), E498-E505. https://doi.org/10.1073/pnas.1103190108
  62. Saraswathy, N., & Ramalingam, P. (2011). Genome mapping. In N. Saraswathy & P. Ramalingam (Eds.), Concepts and Techniques in Genomics and Proteomics (pp. 77-93). Woodhead Publishing. https://doi.org/10.1533/9781908818058.77
  63. Schmidt, T., & Heslop-Harrison, J. S. (1998). Genomes, genes and junk: The large-scale organization of plant chromosomes. Trends in Plant Science, 3(5), 195-199. https://doi.org/10.1016/S1360-1385(98)01223-0
  64. Shamim, Z., & Armstrong, S. J. (2020). Using Genome In Situ Hybridization (GISH) to Distinguish the Constituent Genomes of Brassica nigra and B. rapa in the Hybrid B. juncea. In M. Pradillo & S. Heckmann (Eds.), Plant Meiosis: Methods and Protocols (pp. 69-78). Springer. https://doi.org/10.1007/978-1-4939-9818-0_7
  65. Stajič, E., Kiełkowska, A., Murovec, J., & Bohanec, B. (2019). Deep sequencing analysis of CRISPR/Cas9 induced mutations by two delivery methods in target model genes and the CENH3 region of red cabbage (Brassica oleracea var. Capitata f. Rubra). Plant Cell, Tissue and Organ Culture (PCTOC), 139(2), 227-235. https://doi.org/10.1007/s11240-019-01665-9
  66. Stoler, S., Keith, K. C., Curnick, K. E., & Fitzgerald-Hayes, M. (1995). A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis. Genes & Development, 9(5), 573-586. https://doi.org/10.1101/gad.9.5.573
  67. Talbert, P. B., Masuelli, R., Tyagi, A. P., Comai, L., & Henikoff, S. (2002). Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. The Plant Cell, 14(5), 1053-1066. https://doi.org/10.1105/tpc.010425
  68. Tek, A. L., Stevenson, W. R., Helgeson, J. P., & Jiang, J. (2004). Transfer of tuber soft rot and early blight resistances from Solanum brevidens into cultivated potato. TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik, 109(2), 249-254. https://doi.org/10.1007/s00122-004-1638-4
  69. Tek, A. L., Song, J., Macas, J., & Jiang, J. (2005). Sobo, a Recently Amplified Satellite Repeat of Potato, and Its Implications for the Origin of Tandemly Repeated Sequences. Genetics, 170(3), 1231-1238. https://doi.org/10.1534/genetics.105.041087
  70. Tek, A. L., Kashihara, K., Murata, M., & Nagaki, K. (2010). Functional centromeres in soybean include two distinct tandem repeats and a retrotransposon. Chromosome Research, 18(3), 337-347. https://doi.org/10.1007/s10577-010-9119-x
  71. Tek, A.L. (2013, Eylül). Moleküler sitogenetik yöntemlerle bitki genom analizi. Konya Tarla Bitkileri Kongresi. Konya.
  72. Tek, A. L., Stupar, R. M., & Nagaki, K. (2015). Modification of centromere structure: A promising approach for haploid line production in plant breeding. Turkish Journal of Agriculture and Forestry, 39(4), 557-562. https://doi.org/10.3906/tar-1405-137
  73. Varshney, R. K., & May, G. D. (2012). Next-generation sequencing technologies: Opportunities and obligations in plant genomics. Briefings in Functional Genomics, 11(1), 1-2. https://doi.org/10.1093/bfgp/els001
  74. Vats, S., Kumawat, S., Kumar, V., Patil, G. B., Joshi, T., Sonah, H., Sharma, T. R., & Deshmukh, R. (2019). Genome Editing in Plants: Exploration of Technological Advancements and Challenges. Cells, 8(11), 1386. https://doi.org/10.3390/cells8111386
  75. Wang, G., Zhang, X., & Jin, W. (2009). An overview of plant centromeres. Journal of Genetics and Genomics, 36(9), 529-537. https://doi.org/10.1016/S1673-8527(08)60144-7
  76. Yu, W., Han, F., Gao, Z., Vega, J. M., & Birchler, J. A. (2007). Construction and behavior of engineered minichromosomes in maize. Proceedings of the National Academy of Sciences, 104(21), 8924-8929. https://doi.org/10.1073/pnas.0700932104
  77. Yu, W., Yau, Y.-Y., & Birchler, J. A. (2016). Plant artificial chromosome technology and its potential application in genetic engineering. Plant Biotechnology Journal, 14(5), 1175-1182. https://doi.org/10.1111/pbi.12466
  78. Zhong, C. X., Marshall, J. B., Topp, C., Mroczek, R., Kato, A., Nagaki, K., Birchler, J. A., Jiang, J., & Dawe, R. K. (2002). Centromeric retroelements and satellites interact with maize kinetochore protein CENH3. The Plant Cell, 14(11), 2825-2836. https://doi.org/10.1105/tpc.006106