Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2009 / Cilt: 33 - Sayı: 2

Serum Adenosine Deaminase Activity in Domestic Animals: Reference Values

Sayfa
137–141
Yayın Tarihi
2009-02-01
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As a result, determination of serum normal ADA and its isoenzyme activities in domestic animals will be useful for scientists who want to investigate ADA activity in future in different diseases.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:This study was aimed to determine normal serum adenosine deaminase (ADA) activity in domestic animals in both sexes and that were considered healthy on the basis of clinical and laboratory examinations.
📊
Temel Bulgular & Veri:In this study, 262 non-pregnant animals of both sexes, belonging to 5 species [cattle (n = 50), sheep (n = 65), goat (n = 52), dog (n = 55), and cat (n = 40)] were used.
💡
Sonuç & Katkı:As a result, determination of serum normal ADA and its isoenzyme activities in domestic animals will be useful for scientists who want to investigate ADA activity in future in different diseases.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Adenosine deaminase · reference value · domestic animals

Özet

This study was aimed to determine normal serum adenosine deaminase (ADA) activity in domestic animals in both sexes and that were considered healthy on the basis of clinical and laboratory examinations. In this study, 262 non-pregnant animals of both sexes, belonging to 5 species [cattle (n = 50), sheep (n = 65), goat (n = 52), dog (n = 55), and cat (n = 40)] were used. Serum total ADA and ADA1 isoenzyme activities were found to be 6.34 ± 0.31 IU/l and 6.34 ± 0.31 IU/l in cattle, 7.57 ± 0.30 IU/l and 7.31 ± 0.47 IU/l in sheep, 7.52 ± 0.36 IU/l and 6.44 ± 0.72 IU/l in goat, 2.56 ± 0.13 IU/l and 2.03 ± 0.30 IU/l in dogs, 23.36 ± 1.59 IU/l and 21.71 ± 2.13 IU/l in cats, respectively. The serum levels of ADA2 were low in sheep, goats, dogs, and cats, whereas in these species ADA1 was high. Furthermore, there was no serum ADA2 activity in cattle. Additionally, there were no significant differences between genders in ADA activities in all species. As a result, determination of serum normal ADA and its isoenzyme activities in domestic animals will be useful for scientists who want to investigate ADA activity in future in different diseases.

Abstract

This study was aimed to determine normal serum adenosine deaminase (ADA) activity in domestic animals in both sexes and that were considered healthy on the basis of clinical and laboratory examinations. In this study, 262 non-pregnant animals of both sexes, belonging to 5 species [cattle (n = 50), sheep (n = 65), goat (n = 52), dog (n = 55), and cat (n = 40)] were used. Serum total ADA and ADA1 isoenzyme activities were found to be 6.34 ± 0.31 IU/l and 6.34 ± 0.31 IU/l in cattle, 7.57 ± 0.30 IU/l and 7.31 ± 0.47 IU/l in sheep, 7.52 ± 0.36 IU/l and 6.44 ± 0.72 IU/l in goat, 2.56 ± 0.13 IU/l and 2.03 ± 0.30 IU/l in dogs, 23.36 ± 1.59 IU/l and 21.71 ± 2.13 IU/l in cats, respectively. The serum levels of ADA2 were low in sheep, goats, dogs, and cats, whereas in these species ADA1 was high. Furthermore, there was no serum ADA2 activity in cattle. Additionally, there were no significant differences between genders in ADA activities in all species. As a result, determination of serum normal ADA and its isoenzyme activities in domestic animals will be useful for scientists who want to investigate ADA activity in future in different diseases.

🔖

Bu Makaleye Atıf Yap

ALTUĞ, N., YÜKSEK, N., AĞAOĞLU, Z., KELEŞ, İ. (2009). Serum Adenosine Deaminase Activity in Domestic Animals: Reference Values. Turkish Journal of Veterinary and Animal Sciences, Cilt: 33 - Sayı: 2, 137–141. https://ajindex.com/articles/122039

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (13)

  1. Gakis, C., Calia, G.M., Naitana, A.G.V., Ortu, A.R., Contu, A.: Serum and pleural adenosine deaminase activity. Correct interpretation of the findings. Chest, 1991; 99: 1555-1556.
  2. Ungerer, J.P.J., Oosthuizen, H.M., Retief, J.H., Bissbort, S.H.: Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Chest, 1994; 106: 33-37.
  3. Bremer, H., Bauer, I., Brock, J.: Adenosine deaminase activity and immune dysfunction. Allerg. Immunol. (Leipz), 1981; 27: 3-13. (article in German with an abstract in English.) Klockars, M., Kleemola, M., Leinonen, M., Koskela, M.: Serum adenosine deaminase in viral and bacterial pneumonia. Chest, 1991; 99: 623-626.
  4. Taher-uz-Zaman, Habibullah, C.M., Saleem, Y.: Decreased adenosine deaminase activity in peripheral lymphocytes of patients suffering from amebic liver abscess. Arch. Med. Res., 1993; 24: 203-204.
  5. Yasuda, J., Tanabe, T., Hashimoto, A., Too, K.: Adenosine deaminase (ADA) activity in tissues and sera from normal and leukaemic cattle. Br. Vet. J., 1996; 152: 485-488.
  6. Hirschberger, J., Koch, S.: Validation of the determination of the activity of adenosine deaminase in the body effusions of cat. Res. Vet. Sci., 1995; 59: 226-229.
  7. Altuğ, N., Ağaoğlu, Z.T., Yüksek, N., Kaya, A., Keleş, İ.: Adenosine deaminase in the diagnosis of white muscle diseases in lambs. Med. Weter., 2006; 62: 1007-1010.
  8. Rodriguez, J.Z., Gonzalez, J.G.: Activity of enzymes involved in energy metabolism of Churra breed lambs, and changes caused by enzootic muscular dystrophy. Ann. Fac. Vet. Leon, 1975; 21: 409-419.
  9. Hirschberger, J., Koch, S.: Validation of an adenosine deaminase assay and its use in the evaluation of body fluids in dogs. Vet. Clin. Pathol., 1996; 25: 100-104.
  10. Altuğ, N., Yüksek, N., Ağaoğlu, Z.T., Özkan, C.: Decreased serum adenosine deaminase activities in Van cats with feline retrovirus infections. Med. Weter., 2007; 63: 184-186.
  11. Altug, N., Agaoglu, Z.T.: Investigation on the relationship between lymphocyte subsets, immunoglobulin levels and adenosine deaminase activities in immunosuppressive dose methylprednisolone treated dogs. Bull. Vet. Inst. Pulawy, 2007; 51: 109-115.
  12. Giusti, G., Galanti, B.: Colorimetric Method. In: Bergmeyer, H.U., Ed., Methods of Enzymatic Analysis. Verlag Chemie, Weinheim. 1984; 315-323.
  13. Kolb, E., Lippmann, R., Schwabe, H., Kirbach, H., Kiracke, A., Leo, M., Wahren, W., Vallentin, G.: The concentration of ascorbic acid, total protein, alpha-amino N, glucose, 3-hydroxybutyrate and cho