Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2012 / Cilt: 36 - Sayı: 1

Congenital lymphoma of B-cell lineage in a newborn calf

Sayfa
77–83
Yayın Tarihi
2012-01-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.

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Amaç & Hipotez:In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described.
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Temel Bulgular & Veri:A histopathological examination showed atypical lymphoid cells separated by connective tissue.
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Sonuç & Katkı:The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: B-cell · calf · congenital

Özet

In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described. A large mass was seen on the head of the calf at birth. At necropsy, multiple masses were found on the skin and internal organs. A histopathological examination showed atypical lymphoid cells separated by connective tissue. None of the tumor cells showed a positive reaction to CD3, but the cells were immunopositive for CD79acy. A CD45+ reaction confirmed a hematopoietic origin of the neoplasm. Tumor cells were also positive for lambda light chain IgG (l IgG). Proliferating cell nuclear antigen (PCNA) immunostaining showed diffuse nuclear positivity. Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) staining found numerous apoptotic bodies. The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.

Abstract

In this report, congenital lymphoma of B-cell lineage in a Brown Swiss calf is described. A large mass was seen on the head of the calf at birth. At necropsy, multiple masses were found on the skin and internal organs. A histopathological examination showed atypical lymphoid cells separated by connective tissue. None of the tumor cells showed a positive reaction to CD3, but the cells were immunopositive for CD79acy. A CD45+ reaction confirmed a hematopoietic origin of the neoplasm. Tumor cells were also positive for lambda light chain IgG (l IgG). Proliferating cell nuclear antigen (PCNA) immunostaining showed diffuse nuclear positivity. Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) staining found numerous apoptotic bodies. The neoplasm was diagnosed as a congenital lymphoma of B-cell lineage.

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Bu Makaleye Atıf Yap

BEYTUT, E., ÖZBA, B. (2012). Congenital lymphoma of B-cell lineage in a newborn calf. Turkish Journal of Veterinary and Animal Sciences, Cilt: 36 - Sayı: 1, 77–83. https://ajindex.com/articles/121876

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Kaynakça (11)

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