Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2011 / Cilt: 35 - Sayı: 2

Duration of immunity following the administration of oil-based avian influenza H5N1 vaccine in layers

Sayfa
75–77
Yayın Tarihi
2011-02-01
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The study showed that a booster dose at day 21 produced a high protective AI antibody titre in birds that minimises the stress of repeated shots of aqueous vaccine.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Avian influenza (AI) occurs worldwide and causes tremendous economic losses.
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Temel Bulgular & Veri:In the present study, an oil-based vaccine created by using Montanide ISA 70 MVG, was prepared and the duration of immunity checked at different time intervals.
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Sonuç & Katkı:The study showed that a booster dose at day 21 produced a high protective AI antibody titre in birds that minimises the stress of repeated shots of aqueous vaccine.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Avian influenza · Montanide ISA 70 MVG · cumulative mean titre

Özet

Avian influenza (AI) occurs worldwide and causes tremendous economic losses. The disease is characterised by respiratory signs, depression, and reduced food and water intake. In the present study, an oil-based vaccine created by using Montanide ISA 70 MVG, was prepared and the duration of immunity checked at different time intervals. For this purpose, the cumulative mean titre (CMT) was calculated after employing haemagglutination inhibition test in 50 pullets at day zero before vaccination and then inoculated 0.3 mL of emulsified vaccine subcutaneously in 40 birds while 10 birds were kept non-vaccinated as a control group throughout the experiment. On day 21, a booster dose of 0.5 mL emulsified AI vaccine was injected into the vaccinated birds that produced highest CMT at day 63 and maintained the protective antibody titre on day 84, 105, 126, 152, 182, and 228 in layers. The study showed that a booster dose at day 21 produced a high protective AI antibody titre in birds that minimises the stress of repeated shots of aqueous vaccine.

Abstract

Avian influenza (AI) occurs worldwide and causes tremendous economic losses. The disease is characterised by respiratory signs, depression, and reduced food and water intake. In the present study, an oil-based vaccine created by using Montanide ISA 70 MVG, was prepared and the duration of immunity checked at different time intervals. For this purpose, the cumulative mean titre (CMT) was calculated after employing haemagglutination inhibition test in 50 pullets at day zero before vaccination and then inoculated 0.3 mL of emulsified vaccine subcutaneously in 40 birds while 10 birds were kept non-vaccinated as a control group throughout the experiment. On day 21, a booster dose of 0.5 mL emulsified AI vaccine was injected into the vaccinated birds that produced highest CMT at day 63 and maintained the protective antibody titre on day 84, 105, 126, 152, 182, and 228 in layers. The study showed that a booster dose at day 21 produced a high protective AI antibody titre in birds that minimises the stress of repeated shots of aqueous vaccine.

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Bu Makaleye Atıf Yap

NISAR, M., RASHID*, A., IQBAL, M. (2011). Duration of immunity following the administration of oil-based avian influenza H5N1 vaccine in layers. Turkish Journal of Veterinary and Animal Sciences, Cilt: 35 - Sayı: 2, 75–77. https://ajindex.com/articles/121614

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Kaynakça (5)

  1. Charlton, B.R.: Avian Disease Manual. 2000; 5th Ed. International book distributing Co in association of American Association of Avian Pathologists. 2. Capua, I., Margangon, S.: Th e challenge of controlling notifi able avian infl uenza by means of vaccination. Avian Dis. 2007; 51: 317-322. Anjum A.D.: Poultry Diseases. 2nd Ed. Waseem Impex Corporation and VetAg Publications. 1997; 57-61.
  2. Alexander, N.J., Machova, J., Hornickova, M., Tomcin, M., Nasi, I., Horyna, B., Holko. I.: Highly pathogenic avian infl uenza virus subtype H5N1 in Mute swan in the Czech Republic. Vet. Microbiol., 2007; 120: 9-16.
  3. Swayne, D.E., Lee, C.W., Spackman, E.: Inactivated North American and European H5N2 avian infl uenza virus vaccines protect chickens from Asian H5N1 high pathogenicity avian infl uenza virus. Avian Pathol. 2006; 35: 141-146.
  4. Stone, H.D.: Effi cacy of avian infl uenza oil-emulsion vaccines in chicken of various ages. Avian Dis., 1987; 31: 484-490.
  5. Hwang, S.D., Kim, H.S., Cho, S.W., Seo, S.H.: Single dose of oil- adjuvanted inactivated vaccine protects chickens from lethal infections of highly pathogenic H5N1 infl uenza virus. Vaccine 2011; 29: 2178-2186.