Dergiler / Kocatepe Tıp Dergisi / 2022 / Cilt: 23 Sayı: 4

DİSLİPİDEMİ VE COVİD 19 ENFEKSİYON RİSKİ ARASINDAKİ İLİŞKİ

THE RELATIONSHIP BETWEEN DYSLIPIDEMIA AND THE RISK OF COVID 19 INFECTION

Mustafa Kuzeytemiz(bursa yüksek ihtisas eğitim araştırma hastanesi)0000-0002-3316-2490
Sayfa
436–440
Yayın Tarihi
2022-10-17
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BULGULAR: İki grup arasında yaş, cinsiyet ve laboratuvar özellikleri açısından fark yoktu.

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Amaç & Hipotez:AMAÇ: Son zamanlarda ortaya çıkan koronavirüs (COVID-19) salgını, küresel bir halk sağlığı sorunu haline gelmiştir.
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Temel Bulgular & Veri:Hipertansiyon, diabetes mellitus, obezite, kronik kalp ve akciğer hastalıkları, COVID-19 enfeksiyonu ve ciddi COVID-19 hastalığı gelişme riskini artırır.
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Sonuç & Katkı:BULGULAR: İki grup arasında yaş, cinsiyet ve laboratuvar özellikleri açısından fark yoktu.
🔬Tür:Laboratuvar & Saha Deneyi
📍Kapsam:19 hasta
⚙️Değişkenler:Covid-19 Virüs · Dislipidemi · Risk faktörleri

Özet

AMAÇ: Son zamanlarda ortaya çıkan koronavirüs (COVID-19) salgını, küresel bir halk sağlığı sorunu haline gelmiştir. Hipertansiyon, diabetes mellitus, obezite, kronik kalp ve akciğer hastalıkları, COVID-19 enfeksiyonu ve ciddi COVID-19 hastalığı gelişme riskini artırır. Bu çalışmada; hiperlipideminin tek başına COVID-19 enfeksiyonu gelişme riskini artırıp artırmadığını amaçladık. GEREÇ VE YÖNTEM: Bu çalışmaya COVID-19 tanısı ile hastaneye yatırılan ve herhangi bir kronik hastalığı olmayan 134 hasta ile 122 sağlıklı kontrol alındı. Hasta grubunun başvurudan önceki son 6 aydaki lipid değerlerinin ortalaması hesaplandı. Kontrol grubunun da yine son 6 aylık lipid parametrelerinin ortalaması alındı. BULGULAR: İki grup arasında yaş, cinsiyet ve laboratuvar özellikleri açısından fark yoktu. COVID-19 hastaları, kontrol deneklerine kıyasla önemli ölçüde daha yüksek trigliserit ve düşük yoğunluklu lipoprotein kolesterol değerlerine ve önemli ölçüde düşük yüksek yoğunluklu lipoprotein kolesterol seviyelerine sahipti (p <0.01). SONUÇ: Dislipidemi ve COVID-19 ile ilgili mevcut araştırmalar sınırlı olmakla birlikte, bulgularımız serum kolesterol düzeylerinin COVID-19 gelişme riski ile önemli ölçüde ilişkili olduğunu göstermektedir.

Abstract

OBJECTIVE: The recent coronavirus disease 2019 (COVID-19) outbreak has become a worldwide public health problem. Hypertension, diabetes mellitus, obesity, chronic heart and lung diseases increase the risk of development of COVID-19 infection and severe COVID-19 disease. In this study; we aimed to investigate whether hyperlipidemia alone increases the risk of development of COVID-19 infection. MATERIAL AND METHODS: One hundred-thirty four patients who were hospitalized with the diagnosis of COVID-19 and did not have any chronic disease and one hundred-twenty-two healthy controls were included in this study. The average of the lipid values of the patient group in the last 6 months before admission was calculated. Likewise, the average of the lipid parameters of the control group in the last 6 months was taken. RESULTS: There were no differences between two groups with regard to age, gender, and laboratory characteristics. Triglyceride and Low-density lipoprotein cholesterol values were significantly higher and High-density lipoprotein cholesterol levels were significantly lower in the COVID-19 patients compared to the control subjects (p < 0.01). CONCLUSIONS: Although research on the association of dyslipidemia with COVID-19 is still insufficient, our findings show that serum cholesterol levels are significantly associated with the risk of COVID-19 infection.

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Bu Makaleye Atıf Yap

Kuzeytemiz, M. (2022). DİSLİPİDEMİ VE COVİD 19 ENFEKSİYON RİSKİ ARASINDAKİ İLİŞKİ. Kocatepe Tıp Dergisi, Cilt: 23 Sayı: 4, 436–440. https://doi.org/10.18229/kocatepetip.962183

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