KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2015 / Cilt: 39 - Sayı: 3

The genetic diversity of both FecB gene and microsatellite GC101is associated with reproduction selection in sheep

ZHANGYUAN PAN
BAOYUN ZHANG
WENPING HU
RAN DI
QIUYUE LIU
XIANGYU WANG
DEHUA YIN
PINGQING WANG
MINGXING CHU
Sayfa
254–260
Yayın Tarihi
2015-08-13
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The differentiation of GC101 allele distribution between Chinese sheep and western sheep also indicated that the FecB of Chinese sheep might be derived from Chinese local areas.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:The aims of study were to reveal the changes in genetic diversity in reproduction selection of sheep.
📊
Temel Bulgular & Veri:Genetic polymorphisms of microsatellite GC101 locus and its linkage with the FecB gene were detected in Chinese local sheep (Small Tail Han and Hu sheep) and western sheep (Texel and Dorset) breeds.
💡
Sonuç & Katkı:The differentiation of GC101 allele distribution between Chinese sheep and western sheep also indicated that the FecB of Chinese sheep might be derived from Chinese local areas.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Sheep · GC101 · FecB gene

Özet

The aims of study were to reveal the changes in genetic diversity in reproduction selection of sheep. Genetic polymorphisms of microsatellite GC101 locus and its linkage with the FecB gene were detected in Chinese local sheep (Small Tail Han and Hu sheep) and western sheep (Texel and Dorset) breeds. There was the same FecB mutation (A746G) in both Small Tail Han and Hu sheep as that in Booroola Merino ewes, but not in Texel and Dorset sheep. Seven alleles, from 192 bp to 210 bp, and 20 genotypes were detected at the GC101 locus in 447 individuals totally. The preponderant allele was 200 bp for Chinese sheep and 202 bp for western sheep.? Linkage analysis showed that there was strong linkage disequilibrium between the 200-bp allele of the GC101 locus and the B allele of the FecB gene (r2 = 0.639). These results preliminarily implied that both the 200-bp allele of the GC101 locus and the B allele of FecB had been reinforced in reproduction selection of Chinese sheep. The differentiation of GC101 allele distribution between Chinese sheep and western sheep also indicated that the FecB of Chinese sheep might be derived from Chinese local areas.

Abstract

The aims of study were to reveal the changes in genetic diversity in reproduction selection of sheep. Genetic polymorphisms of microsatellite GC101 locus and its linkage with the FecB gene were detected in Chinese local sheep (Small Tail Han and Hu sheep) and western sheep (Texel and Dorset) breeds. There was the same FecB mutation (A746G) in both Small Tail Han and Hu sheep as that in Booroola Merino ewes, but not in Texel and Dorset sheep. Seven alleles, from 192 bp to 210 bp, and 20 genotypes were detected at the GC101 locus in 447 individuals totally. The preponderant allele was 200 bp for Chinese sheep and 202 bp for western sheep.? Linkage analysis showed that there was strong linkage disequilibrium between the 200-bp allele of the GC101 locus and the B allele of the FecB gene (r2 = 0.639). These results preliminarily implied that both the 200-bp allele of the GC101 locus and the B allele of FecB had been reinforced in reproduction selection of Chinese sheep. The differentiation of GC101 allele distribution between Chinese sheep and western sheep also indicated that the FecB of Chinese sheep might be derived from Chinese local areas.

🔖

Bu Makaleye Atıf Yap

PAN, Z., ZHANG, B., HU, W., DI, R., LIU, Q., WANG, X., YIN, D., WANG, P., CHU, M. (2015). The genetic diversity of both FecB gene and microsatellite GC101is associated with reproduction selection in sheep. Turkish Journal of Veterinary and Animal Sciences, Cilt: 39 - Sayı: 3, 254–260. https://ajindex.com/articles/121382

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (11)

  1. Mulsant P, Lecerf F, Fabre S, Schibler L, Monget P, Lanneluc I, Pisselet C, Riquet J, Monniaux D, Callebaut I et al. Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Merino ewes. P Natl Acad Sci USA 2001; 98: 5104–5109.
  2. Davis GH, Montgomery GW, Allison AJ, Kelly RW, Bray AR. Segregation of a major gene influencing fecundity in progeny of Booroola sheep. New Zeal J Agr Res 1982; 25: 525–529.
  3. Piper LR, Bindon BM. The Booroola Merino and the performance of medium non-Peppin crosses at Armidale. In: Piper LR, Bindon BM, Nethery RD, editors. The Booroola Merino. Melbourne, Australia: CSIRO; 1982. pp. 9–20.
  4. Wilson T, Wu XY, Juengel JL, Ross IK, Lumsden JM, Lord EA, Dodds KG, Walling GA, McEwan JC, O’Connell AR et al. Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biol Reprod 2001; 64: 1225–1235. Bindon BM. Reproductive biology of the Booroola Merino sheep. Aust J Biol Sci 1984; 37: 163–190.
  5. Piper LR, Bindon BM, Davis GH. Single gene inheritance of the high litter size of the Booroola Merino. In: Land RB, Robinson DW, editors. Genetics of Reproduction in Sheep. London, UK: Butterworths;1985. pp. 115–125.
  6. Davis GH, Galloway SM, Ross IK, Gregan SM, Ward J, Nimbkar BV, Ghalsasi PM, Nimbkar C, Gray GD, Subandriyo et al. DNA tests in prolific sheep from eight countries provide new evidence on origin of the Booroola (FecB) mutation. Biol Reprod 2002; 66: 1869–1874.
  7. Kumar S, Mishra AK, Kolte AP, Dash SK, Karim SA. Screening for Booroola (FecB) and Galway (FecXG) mutations in Indian sheep. Small Ruminant Res 2008; 80: 57–61.
  8. Roy J, Polley S, De S, Mukherjee A, Batabyal S, Pan S, Brahma B, Datta TK, Goswami SL. Polymorphism of fecundity genes (FecB, FecX, and FecG) in the Indian Bonpala sheep. Anim Biotechnol 2011; 22: 151–162.
  9. Mahdavi M, Nanekarani S, Hosseini SD. Mutation in BMPR-IB gene is associated with litter size in Iranian Kalehkoohi sheep. Anim Reprod Sci 2014; 147: 93–98.
  10. Chu MX, Liu ZH, Jiao CL, He YQ, Fang L, Ye SC, Chen GH, Wang JY. Mutations in BMPR-IB and BMP-15 genes are associated with litter size in Small Tailed Han sheep (Ovis aries). J Anim Sci 2007; 85: 598–603.
  11. Davis GH, Balakrishnan L, Ross IK, Wilson T, Galloway SM, Lumsden BM, Hanrahan JP, Mullen M, Mao XZ, Wang GL et al. Investigation of the Booroola (FecB) and Inverdale (FecXI) mutations in 21 prolifi