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Dergiler / Turkish Journal of Veterinary and Animal Sciences / 2017 / Cilt: 41 - Sayı: 3

Intestinal barrier and mucosal immunity in broilers, Thai Betong, and native Thai Praduhangdum chickens

Sirin THEERAWATANASIRIKUL
Nunyarat KOOMKRONG
Autchara KAYAN
Chaiwat BOONKAEWWAN
Sayfa
357–364
Yayın Tarihi
2017-06-12
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

TJ localizations together with intestinal morphology and mucosal immunity can be utilized as biological markers for gut health.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The intestinal barrier includes physical and chemical components for preventing the invasion of pathogenic and toxic agents.
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Temel Bulgular & Veri:Intestinal samples from 40 chickens of each breed were collected.
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Sonuç & Katkı:TJ localizations together with intestinal morphology and mucosal immunity can be utilized as biological markers for gut health.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Chicken · intestinal barrier · intestinal morphology

Abstract

The intestinal barrier includes physical and chemical components for preventing the invasion of pathogenic and toxic agents. The aim of this study was to investigate small intestinal morphology, antimicrobial peptides, and tight junction (TJ) distribution among broilers, Thai Betong chickens, and native Thai Praduhangdum chickens. Intestinal samples from 40 chickens of each breed were collected. The results of the histological and morphological examination revealed that the duodenum of all breeds had the maximum villus height compared to the other parts. The intestinal tract of both Betong and Praduhangdum chickens was low in the number of mucin and goblet cells. In broilers, the intestinal surface mucins correlated with the number of β-defensin-positive Paneth cells. Claudin-1 protein was observed in the cytoplasm of the epithelium in all breeds, with the highest intensity of claudin-1 staining detected in the intestinal cells of the ileum. Localization of occludin was higher in the broilers in all intestinal segments than in the native Thai chickens. In conclusion, the broilers exhibited a large amount of TJ proteins and mucosal immunity as compared to native Thai-breed chickens. TJ localizations together with intestinal morphology and mucosal immunity can be utilized as biological markers for gut health.

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Bu Makaleye Atıf Yap

THEERAWATANASIRIKUL, S., KOOMKRONG, N., KAYAN, A., BOONKAEWWAN, C. (2017). Intestinal barrier and mucosal immunity in broilers, Thai Betong, and native Thai Praduhangdum chickens. Turkish Journal of Veterinary and Animal Sciences, Cilt: 41 - Sayı: 3, 357–364. https://ajindex.com/articles/121345

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Kaynakça (10)

  1. Bischoff S, Barbara G, Buurman W, Ockhuizen T, Schulzke JD, Serino M, Tilg H, Watson A, Wells JW. Intestinal permeability–a new target for disease prevention and therapy. BMC Gastroenterology 2014; 14: 189. Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE et al. The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system. Immunol Rev 2014; 260: 8-20.
  2. Ulluwishewa D, Anderson RC, McNabb WC, Moughan PJ, Wells JM, Roy NC. Regulation of tight junction permeability by intestinal bacteria and dietary components. J Nutri 2011; 141: 769-776.
  3. Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 1998; 273: 29745-29753.
  4. Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J, Blasig IE. Structure and function of claudins. Biochim Biophys Acta 2008; 1778: 631-645.
  5. Cataliota RM, Maggi MA, Giuliani S. Intestinal epithelial barrier dysfunction in disease and possible therapeutical interventions. Curr Med Chem 2011; 18: 398-426.
  6. Chen J, Tellez G, Richards JD, Escobar J. Identification of potential biomarkers for gut barrier failure in broiler chickens. Frontiers in Veterinary Science 2015; 2: 1-10.
  7. Shao Y, Guo Y, Wang Z. β-1,2/1,6-Glucan alleviated intestinal mucosal barrier impairment of broiler chickens challenged with Salmonella enterica serovar Typhimurium. Poultry Sci 2013; 92: 1764 -1773. Jaturasitha S, Srikanchai T, Kreuzer M, Wicke M. Differences in carcass and meat characteristics between chicken indigenous to northern Thailand (black-boned and Thai native) and imported extensive breeds (Bresse and Rhode Island Red). Poultry Sci 2008; 87: 160-169.
  8. Youssao IAK, Alkoiret IT, Dahouda M, Assogba MN, Idrissou ND, Kayang BB, Yapi-Gnaoré V, Assogba HM, Houinsou AS, Ahounou SG et al. Comparison of growth performance, carcass characteristics and meat quality of Benin indigenous chickens and Label Rouge (T55×SA51). Afr J Biotechnol 2012; 11: 15569-15579.
  9. Theerawatanasirikul S, Sailasuta A, Thanawongnuwech R, Nakbed T, Charngkaew K, Gunnaporn S. Differential expression patterns of proteins involved in epidermal proliferation and differentiation in canine atopic dermatitis. Thai J Vet Med 2012; 42: 287-296.
  10. Smirnov A, Sklan D, Uni, Z. Mucin dynamics in the chick sm