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Dergiler / Çocuk Dergisi / 2026 / Cilt: 23 Sayı: 4

Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria

Olayinka Rasheed Ibrahim(University of Ilorin Teaching Hospital, Department of Paediatric)0000-0002-2621-6593
Olajide Aladesua(Federal Teaching Hospital, Department of Paediatrics)0000-0001-7034-0789
Michael Abel Alao(University College Hospital & University of Ibadan, Department of Paediatrics)0000-0003-0109-4435
Abdurrazzaq Alege(Federal Teaching Hospital, Department of Paediatrics)0000-0003-3648-5479
Sayfa
327–333
Yayın Tarihi
2024-02-20
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Fever was associated with outcomes, while serum creatinine and urea levels were elevated among non-survivors.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Studies on acute glomerulonephritis (AGN) in Nigeria described the epidemiological profile without an in-depth analysis of variables associated with outcomes.
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Temel Bulgular & Veri:Material and Methods: This prospective cross-sectional study was conducted between 1st January 2018 and 31st December 2019 at a tertiary health facility in northwestern Nigeria.
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Sonuç & Katkı:Fever was associated with outcomes, while serum creatinine and urea levels were elevated among non-survivors.
🔬Tür:Araştırma Makalesi
📍Kapsam:2018 Verileri
⚙️Değişkenler:Child · Acute Glomerulonephritis · Outcomes

Abstract

Objective: Studies on acute glomerulonephritis (AGN) in Nigeria described the epidemiological profile without an in-depth analysis of variables associated with outcomes. Herein, we describe the profile and factors associated with hospitalization outcomes (discharge or death) among childhood AGNs at a health facility in northwestern Nigeria. Material and Methods: This prospective cross-sectional study was conducted between 1st January 2018 and 31st December 2019 at a tertiary health facility in northwestern Nigeria. The diagnosis of AGN was based on a clinical diagnosis. We also obtained relevant history, clinical, and laboratory features. Results: Thirty-five children were admitted with AGN during the study period. The mean age was 7.7 ± 3.3 years. Most were aged 5 to 10 years (23; 65.7%), male (60.0%), and from a lower socio-economic class (77.2%). The annual incidence of AGN was 11 cases per 1000 children. The most common clinical presentations were generalized body swelling (100.0%), reduced urine output (85.7%), and hypertension (74.3%). The medians (interquartile range) of urea and creatinine were 10.0 (4.50 to 23.90) mmol/L and 85 (67.60 to 204.00) µmol/L, respectively. Among the clinical features, only fever was associated with outcomes, while serum urea and creatinine levels were significantly higher among non-survivors, p<0.05. We recorded four deaths (case fatality rate of 11.4%), two each from congestive cardiac failure and hypertensive encephalopathy. Conclusion: This study shows a high incidence of childhood AGN and mortality in Katsina, northwestern Nigeria. Fever was associated with outcomes, while serum creatinine and urea levels were elevated among non-survivors.

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Bu Makaleye Atıf Yap

Ibrahim, O. R., Aladesua, O., Alao, M. A., Alege, A. (2024). Profile and Outcomes of Children with Acute Glomerulonephritis in Northwestern Nigeria. Çocuk Dergisi, Cilt: 23 Sayı: 4, 327–333. https://doi.org/10.26650/jchild.2023.1231820

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