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Dergiler / Çocuk Dergisi / 2026 / Cilt: 24 Sayı: 3

Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience

Asuman Demirbuğa(İstanbul University, Istanbul Faculty of Medicine, Department of Pediatrics)0000-0001-8928-1555
Sukran Poyrazoglu(İstanbul University, Istanbul Faculty of Medicine, Department of Pediatric Endocrinology)0000-0001-6806-9678
Rüveyde Bundak(University of Kyrenia, Department of Pediatric Endocrinology)0000-0001-5097-6448
Sayfa
154–161
Yayın Tarihi
2025-01-03
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Close monitoring of these children is important to prevent complications.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus (DM), hypertension, and metabolic syndrome (MetS).
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Temel Bulgular & Veri:This study evaluated MetS and type 2 diabetes mellitus (DM) in overweight and obese children.
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Sonuç & Katkı:Close monitoring of these children is important to prevent complications.
🔬Tür:Araştırma Makalesi
📍Kapsam:2000 Verileri
⚙️Değişkenler:Childhood obesity · overweight · metabolic syndrome

Abstract

Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus (DM), hypertension, and metabolic syndrome (MetS). This study evaluated MetS and type 2 diabetes mellitus (DM) in overweight and obese children. Methods: Between 2000 and 2013, 474 obese and overweight children aged <18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated. Results: Of the patients, 50.4% (n = 239) were girls, and the mean age was 10.91±3.06 years. According to the body mass index, 20.5% (n=97) of the patients were overweight and 79.5% (n=377) were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group (p <0.05). MetS was found in 30.8% (n=146) of the patients. The MetS rate was 37.7% (n=142) in the obese patients and 4.1% (n=4) in the overweight patients, and the difference between them was statistically significant (p<0.001) Based on the oral glucose tolerance test; 45 (9.5%) patients had impaired fasting glycaemia, 24 (5%) had impaired glucose tolerance and 4 (0.84%) had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR. Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications.

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Bu Makaleye Atıf Yap

Demirbuğa, A., Poyrazoglu, S., Bundak, R. (2025). Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience. Çocuk Dergisi, Cilt: 24 Sayı: 3, 154–161. https://doi.org/10.26650/jchild.2024.1527424

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