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Dergiler / Çocuk Dergisi / 2026 / Cilt: 25 Sayı: 3

Successful Treatment of MuSK Antibody–Positive Myasthenia Gravis with Rituximab

Arife Derda Yücel Şen(ESKISEHIR OSMANGAZI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NEUROLOGY)0000-0002-2656-5611
Ahmet Baysal(ESKISEHIR OSMANGAZI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NEUROLOGY)0000-0002-5909-1918
Özlem Uğur(ESKISEHIR OSMANGAZI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NEUROLOGY)0000-0001-9257-085X
Kürşat Bora Çarman(ESKISEHIR OSMANGAZI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NEUROLOGY)0000-0002-4629-1873
Coşkun Yarar(ESKISEHIR OSMANGAZI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NEUROLOGY)0000-0001-7462-4578
Sayfa
172–175
Yayın Tarihi
2025-10-31
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We report a pediatric MuSK-MG patient who exhibited a favourable response to rituximab following the ineffectiveness of steroid therapy and acetylcholinesterase inhibitor (AChEI) therapy.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Muscle-specific tyrosine kinase antibody-associated myasthenia gravis (MuSK-MG) is a rare subtype of MG distinguished by recurring relapses and a clinical history unresponsive to conventional therapies.
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Temel Bulgular & Veri:Rituximab, a monoclonal antibody that targets CD20+ B cells, has effectively induced long-term remission in adults.
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Sonuç & Katkı:We report a pediatric MuSK-MG patient who exhibited a favourable response to rituximab following the ineffectiveness of steroid therapy and acetylcholinesterase inhibitor (AChEI) therapy.
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Child · myasthenia gravis · MUSK

Abstract

Muscle-specific tyrosine kinase antibody-associated myasthenia gravis (MuSK-MG) is a rare subtype of MG distinguished by recurring relapses and a clinical history unresponsive to conventional therapies. Rituximab, a monoclonal antibody that targets CD20+ B cells, has effectively induced long-term remission in adults. We report a pediatric MuSK-MG patient who exhibited a favourable response to rituximab following the ineffectiveness of steroid therapy and acetylcholinesterase inhibitor (AChEI) therapy.

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Bu Makaleye Atıf Yap

Şen, A. D. Y., Baysal, A., Uğur, Ö., Çarman, K. B., Yarar, C. (2025). Successful Treatment of MuSK Antibody–Positive Myasthenia Gravis with Rituximab. Çocuk Dergisi, Cilt: 25 Sayı: 3, 172–175. https://doi.org/10.26650/jchild.2025.1704940

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Kaynakça (12)

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