Dergiler / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 6

Restless legs syndrome in multiple sclerosis

Sayfa
1268–1273
Yayın Tarihi
2015-12-04
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

No association was found between RLS and functional system involvement in MS patients.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background/aim: There have been conflicting results in the literature regarding the relationship between functional system involvement, the expanded disability status scale (EDSS), and the presence of restless legs syndrome (RLS) in patients with multiple sclerosis (MS).
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Temel Bulgular & Veri:Materials and methods: Ninety-one patients with MS and 40 patients in a control group (headache, essential tremor, and benign positional paroxysmal vertigo) were studied.
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Sonuç & Katkı:No association was found between RLS and functional system involvement in MS patients.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Multiple sclerosis · restless legs syndrome · EDSS

Özet

Background/aim: There have been conflicting results in the literature regarding the relationship between functional system involvement, the expanded disability status scale (EDSS), and the presence of restless legs syndrome (RLS) in patients with multiple sclerosis (MS). Materials and methods: Ninety-one patients with MS and 40 patients in a control group (headache, essential tremor, and benign positional paroxysmal vertigo) were studied. The patients underwent a complete neurological examination and Kurtzke functional system scores were calculated. In order to assess the temporal relation between the onset of RLS and MS, a semistructured interview guided by a questionnaire about RLS was applied to all of the patients. Results: Sixteen (17.6%) of the patients with MS and 1 (2.5%) patient in the control group had RLS. The prevalence of RLS was higher in patients with MS, compared to the control group (P = 0.018). Among the patients with MS, none of them suffered from RLS before the onset of MS, whereas sixteen patients (16%) suffered RLS after the onset of MS. There was no significant relationship between functional system involvement and the presence of RLS. Conclusion: The prevalence of RLS was higher in MS patients than it was in the control group. No association was found between RLS and functional system involvement in MS patients.

Abstract

Background/aim: There have been conflicting results in the literature regarding the relationship between functional system involvement, the expanded disability status scale (EDSS), and the presence of restless legs syndrome (RLS) in patients with multiple sclerosis (MS). Materials and methods: Ninety-one patients with MS and 40 patients in a control group (headache, essential tremor, and benign positional paroxysmal vertigo) were studied. The patients underwent a complete neurological examination and Kurtzke functional system scores were calculated. In order to assess the temporal relation between the onset of RLS and MS, a semistructured interview guided by a questionnaire about RLS was applied to all of the patients. Results: Sixteen (17.6%) of the patients with MS and 1 (2.5%) patient in the control group had RLS. The prevalence of RLS was higher in patients with MS, compared to the control group (P = 0.018). Among the patients with MS, none of them suffered from RLS before the onset of MS, whereas sixteen patients (16%) suffered RLS after the onset of MS. There was no significant relationship between functional system involvement and the presence of RLS. Conclusion: The prevalence of RLS was higher in MS patients than it was in the control group. No association was found between RLS and functional system involvement in MS patients.

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Bu Makaleye Atıf Yap

SORGUN, M. H., AKSUN, Z., ATALAY, Y. B., YÜCESAN, C. (2015). Restless legs syndrome in multiple sclerosis. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 6, 1268–1273. https://ajindex.com/articles/113735

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Kaynakça (10)

  1. Earley CJ. Restless legs syndrome. N Engl J Med 2003; 348: 2103–2109.
  2. Clemens S, Rye D, Hochmen S. Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective. Neurology 2006; 67: 125–130.
  3. Brown LK, Heffner JE, Obbens EA. Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen. Sleep 2000; 23: 591– 594. 4. Soyoral Y, Sayarlıoğlu H, Tuncel D, Şahin M, Doğan E, Erkoç R. Prevalence and risk factors of restless leg syndrome in a single hemodialysis unit. Turk J Med Sci 2010; 40: 443–446. Allen R. Dopamine and iron in pathophysiology of restless legs syndrome (RLS). Sleep Med 2004; 5: 385–391.
  4. Turjanski N, Lees AJ, Brooks DJ. Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies. Neurology 1999; 52: 932–937.
  5. Ruottinen HM, Partinen M, Hublin C, Bergman J, Haaparanta M, Solin O, Rinne JO. An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. Neurology 2000; 54: 502–504.
  6. Trenkwalder C, Walters AS, Hening WA, Chokroverty S, Antonini A, Dhawan V, Eidelberg D. Positron emission tomographic studies in restless legs syndrome. Mov Disord 1999; 14: 141–145.
  7. Cervenka S, Palhagen SE, Comley RA, Panagiotidis G, Cselenyi Z, Matthews JC, Lai RY, Halldin C, Farde L. Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding. Brain 2006; 129: 2017–2028.
  8. Cirignotta F, Zucconi M, Mondini S. Epidemiologic data on sleep disorders. Presented at the 6th European Congress on Sleep Research. Zurich, Switzerland. 1982. Strang P. The symptom of restless legs. Med J 1967; 1: 1211– 1213. Lavigne GJ, Montplaisir JY. Restless legs syndrome and sleep bruxism: prevalence and association among Canadians. Sleep 1994; 17: 739–743.
  9. Phillips B, Young T, Finn L, Asher K, Hening WA, Purvis C. Epidemiology of restless legs symptoms in adults. Arch Internal Med 2000; 160: 2137–2141. National Sleep Foundation. Omnibus Sleep in America Poll. Washington DC, USA: National Sleep Foundation; 2000.
  10. Rothdach AJ, Trenkwalder C, Haberstock J, Keil U, Berger K. Prevalence and risk factors of RLS in an elderly population: the MEMO study. Memory and morbidity in Augsburg elderly. Neurology 2000; 54: 1064 – 1068. Sevim S, Dogu O, Camdeviren H, Bugdayci R, Sasmaz T, Kaleagasi H, Aral M, Helvaci I. Unexpectedly low prevalence and unusual characteristics of