Dergiler / Turkish Journal of Medical Sciences / 2018 / Cilt: 48 - Sayı: 2

Positive effect of restrictions on antibiotic consumption

Sayfa
361–365
Yayın Tarihi
2018-04-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Positive behaviors that were obtained during the restricted period were continued with release of restriction.

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Amaç & Hipotez:Background/aim: This study aimed to examine the change in the etiology of hospital infections with restricting and releasing of group 2 carbapenems (G2C) (meropenem/imipenem/doripenem).
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Temel Bulgular & Veri:Study period 1 (SP-1): Carbapenems were prescribed without restriction by infectious disease specialists.
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Sonuç & Katkı:Positive behaviors that were obtained during the restricted period were continued with release of restriction.
🔬Tür:Araştırma Makalesi
📍Kapsam:2085 Verileri
⚙️Değişkenler:Restriction of carbapenem · antibiotic stewardships · hospital-acquired Acinetobacter infections

Abstract

Background/aim: This study aimed to examine the change in the etiology of hospital infections with restricting and releasing of group 2 carbapenems (G2C) (meropenem/imipenem/doripenem). Materials and methods: This study was planned in three periods. Study period 1 (SP-1): Carbapenems were prescribed without restriction by infectious disease specialists. SP-2: G2C prescription was restricted. SP-3: Carbapenem prescription was released. Results: In total, 4443 cases [1053 in SP-1 (23.7%), 1332 in SP-2 (29.9%), and 2085 in SP-3 (46.9%)] were included in the study. Infection rates were 11%, 6.5%, and 7.9% in SP-1, SP-2, and SP-3, respectively (P = 0.001). Acinetobacter spp.-related hospital infection rates were 3.9%, 1.2%, and 1.8%, in SP-1, SP-2, and SP-3, respectively (P = 0.0001). Infection related mortality in SP-1, SP-2, and SP-3 was 7.3%, 5%, and 3.8%, respectively (P = 0.001). Conclusion: Hospital-acquired Acinetobacter infections, antibiotic consumption, and infection-related mortality were decreased signi cantly with the restriction of G2C. Positive behaviors that were obtained during the restricted period were continued with release of restriction.

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Bu Makaleye Atıf Yap

KARABAY, O., KAYA, G., GÜÇLÜ, E., ÖĞÜTLÜ, A. (2018). Positive effect of restrictions on antibiotic consumption. Turkish Journal of Medical Sciences, Cilt: 48 - Sayı: 2, 361–365. https://ajindex.com/articles/113667

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