Dergiler / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 4

The association between levels of inflammatory markers in autistic children compared to their unaffected siblings and unrelated healthy controls

Sayfa
1047–1053
Yayın Tarihi
2019-08-01
DOI
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Results: Interleukin-6 was found to be significantly higher in the plasma of both autistic children and their siblings compared with the unrelated healthy control group (P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background/aim: Autism spectrum disorder (ASD) describes a range of neurodevelopmental disabilities that impair behavior and communication.
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Temel Bulgular & Veri:The aim of this study is to identify a possible association between interleukin-6, -8, -9, and -10 and tumor necrosis factor alpha (TNF- ∝) in autism among Jordanian children by comparing the plasma levels of these cytokines in autistic children with those of their unaffected siblings and unrelated healthy controls.
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Sonuç & Katkı:Results: Interleukin-6 was found to be significantly higher in the plasma of both autistic children and their siblings compared with the unrelated healthy control group (P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Autism · interleukins · siblings

Abstract

Background/aim: Autism spectrum disorder (ASD) describes a range of neurodevelopmental disabilities that impair behavior and communication. Although it is relatively prevalent, the pathophysiology is still subject to speculation and debate. The aim of this study is to identify a possible association between interleukin-6, -8, -9, and -10 and tumor necrosis factor alpha (TNF- ∝) in autism among Jordanian children by comparing the plasma levels of these cytokines in autistic children with those of their unaffected siblings and unrelated healthy controls. Materials andmethods: In this study, 80 Jordanian children under the age of 12 with diagnosed autism were selected. For comparison, 51 unaffected siblings and 86 unrelated healthy controls were also recruited. Venous blood was collected and interleukin levels in all three groups were investigated. Results: Interleukin-6 was found to be significantly higher in the plasma of both autistic children and their siblings compared with the unrelated healthy control group (P

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Bu Makaleye Atıf Yap

ALZGHOUL, L., ABDELHAMID, S., YANIS, A., QWAIDER, Y., ALDAHABI, M., ALBDOUR, S. (2019). The association between levels of inflammatory markers in autistic children compared to their unaffected siblings and unrelated healthy controls. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 4, 1047–1053. https://ajindex.com/articles/113321

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