Dergiler / Turkish Journal of Medical Sciences / 2020 / Cilt: 50 - Sayı: 1

An evaluation of the effects of caffeic acid phenethyl ester and Ankaferd blood stopper on secondary wound healing of oral mucosal tissue

Sayfa
248–257
Yayın Tarihi
2020-01-01
DOI
—
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Results: Inflammation, vessel dilatation, and haemorrhages were significantly lower in the CAPE group as compared with these parameters in the other groups P

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background/aim: Caffeic acid phenethyl ester CAPE and Ankaferd Blood Stopper ABS are considered to contribute to wound healing.
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Temel Bulgular & Veri:Materials and methods: In total, 63 male Sprague-Dawley rats were used in this study.
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Sonuç & Katkı:Results: Inflammation, vessel dilatation, and haemorrhages were significantly lower in the CAPE group as compared with these parameters in the other groups P
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Wound healing · vascular endothelial growth factor · tumour necrosis factor-inducible gene 6 protein

Abstract

Background/aim: Caffeic acid phenethyl ester CAPE and Ankaferd Blood Stopper ABS are considered to contribute to wound healing. The purpose of this study was to investigate the effect of ABS and CAPE on secondary wound healing of oral mucosal tissue. Materials and methods: In total, 63 male Sprague-Dawley rats were used in this study. The animals were randomly divided into three groups and anaesthetized with ketamine 8 mg/100 g, intraperitoneally : a control group, CAPE group, and ABS group. A full-thickness excisional wound was created using a 4 mm punch biopsy tool. Topical ABS and CAPE were then applied in each group for 7, 14, and 21 days n = 7 in each group . The animals in each group were sacrificed after 7, 14, and 21 days. Palatal specimens were stained with haematoxylin-eosin. Vascular endothelial growth factor VEGF and tumour necrosis factor-inducible gene 6 TSG-6 protein expressions were determined using the Western blot method. Results: Inflammation, vessel dilatation, and haemorrhages were significantly lower in the CAPE group as compared with these parameters in the other groups P

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Bu Makaleye Atıf Yap

GÜL, M., GÜNAY, A., TANIK, A. (2020). An evaluation of the effects of caffeic acid phenethyl ester and Ankaferd blood stopper on secondary wound healing of oral mucosal tissue. Turkish Journal of Medical Sciences, Cilt: 50 - Sayı: 1, 248–257. https://ajindex.com/articles/113246

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Kaynakça (13)

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