Dergiler / İstanbul Tıp Fakültesi Dergisi / 2026 / Cilt: 89 Sayı: 2

ANAPHYLAXIS TO PANTOPRAZOLE AND OMEPRAZOLE WITH CROSS-REACTIVITY TO ALL PROTON PUMP INHIBITORS: IDENTIFICATION OF A SAFE ALTERNATIVE

Ece Şahinoğlu(Ankara University Faculty of Medicine)0000-0002-3422-6433
Sevim Bavbek(ANKARA UNIVERSITY, ANKARA FACULTY OF MEDICINE)0000-0002-7884-0830
Sayfa
145–147
Yayın Tarihi
2026-05-13
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

H2 receptor antagonist famotidine was considered safe after negative results on both the skin prick test (SPT) and oral provocation test (OPT) .

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Proton pump inhibitors (PPIs) are widely prescribed for the management of peptic diseases, including gastroesophageal reflux (GER) and gastric ulcers.
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Temel Bulgular & Veri:A 43-year-old woman was admitted to our inpatient clinic with a history of anaphylactic reactions to both pantoprazole and omeprazole.
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Sonuç & Katkı:H2 receptor antagonist famotidine was considered safe after negative results on both the skin prick test (SPT) and oral provocation test (OPT) .
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Proton pump inhibitors · Anaphylaxis · Hypersensitivity reaction

Abstract

Proton pump inhibitors (PPIs) are widely prescribed for the management of peptic diseases, including gastroesophageal reflux (GER) and gastric ulcers. The risk profile of PPIs is acceptable, and hypersensitivity reactions to PPIs are extremely rare. We present a case in which type I hypersensitivity reactions to all PPIs were confirmed. A 43-year-old woman was admitted to our inpatient clinic with a history of anaphylactic reactions to both pantoprazole and omeprazole. Allergy work-up revealed an IgE-mediated hypersensitivity to all proton pump inhibitors. H2 receptor antagonist famotidine was considered safe after negative results on both the skin prick test (SPT) and oral provocation test (OPT) .

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Bu Makaleye Atıf Yap

Şahinoğlu, E., Bavbek, S. (2026). ANAPHYLAXIS TO PANTOPRAZOLE AND OMEPRAZOLE WITH CROSS-REACTIVITY TO ALL PROTON PUMP INHIBITORS: IDENTIFICATION OF A SAFE ALTERNATIVE. İstanbul Tıp Fakültesi Dergisi, Cilt: 89 Sayı: 2, 145–147. https://doi.org/10.26650/IUITFD.1737119

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Kaynakça (15)

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