Dergiler / Journal of Microbiology and Infectious Diseases / 2021 / Cilt: 11 - Sayı: 01

BK Virus Pneumonia with CMV Colitis in a Kidney Transplant Recipient: Successful Treatment with Non-Cidofovir Based Therapy

Sayfa
36–41
Yayın Tarihi
2021-03-15
DOI
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J Microbiol Infect Dis 2021; 11(1):36-41.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:BK virus (BKV) pneumonia is a rare entity especially seen in immunosuppressed patients, for which cidofovir is the used treatment option.
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Temel Bulgular & Veri:The patient improved clinically except that her kidney function deteriorated.
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Sonuç & Katkı:J Microbiol Infect Dis 2021; 11(1):36-41.
🔬Tür:Araştırma Makalesi
📍Kapsam:2021 Verileri
⚙️Değişkenler:BK virus pneumonia · CMV colitis · Kidney transplantation

Abstract

BK virus (BKV) pneumonia is a rare entity especially seen in immunosuppressed patients, for which cidofovir is the used treatment option. We describe a case of a young female patient who presented for altered kidney function six months following kidney transplantation for focal segmental glomerulosclerosis and was found to have BKV nephritis. Her in-hospital stay was complicated by BKV pneumonia requiring mechanical ventilation, in addition to CMV colitis. She was treated with leflunomide/ciprofloxacin and ganciclovir for her pneumonia and colitis, respectively. The patient improved clinically except that her kidney function deteriorated. Leflunomide/ciprofloxacin combination may constitute an effective and safe alternative to cidofovir for the treatment of BKV pneumonia, in particular when cidofovir is not available. J Microbiol Infect Dis 2021; 11(1):36-41.

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Bu Makaleye Atıf Yap

CHAİTOU, A. R., NASSER, M., KARNIB, H., HAMİEH, A. (2021). BK Virus Pneumonia with CMV Colitis in a Kidney Transplant Recipient: Successful Treatment with Non-Cidofovir Based Therapy. Journal of Microbiology and Infectious Diseases, Cilt: 11 - Sayı: 01, 36–41. https://ajindex.com/articles/111273

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Kaynakça (13)

  1. Reploeg MD, Storch GA, Clifford DB. Bk virus: a clinical review. Clin Infect Dis an Off Publ Infect Dis Soc Am. 2001;33(2):191-202
  2. Park SB, Kwak JH, Lee KT, et al. Polyoma Virus-Associated Nephropathy and Concurrent Cytomegalovirus Infection in the Kidney Transplant Recipients. Transplant Proc. 2006; 38(7):2059-2061
  3. Cordero E, Casasola C, Ecarma R, Danguilan R. Cytomegalovirus disease in kidney transplant recipients: incidence, clinical profile, and risk factors. Transplant Proc. 2012;44(3):694-700
  4. Hariharan S. BK virus nephritis after renal transplantation. Kidney Int. 2006;69(4):655-662
  5. Yapa HMN, McLornan DP, Raj K, et al. Pneumonitis post-haematopoeitic stem cell transplant - cytopathology clinches diagnosis. J Clin Virol Off Publ Pan Am Soc Clin Virol. 2012;55(3):278-281
  6. Yoshimura A, Tsuji T, Kawaji Y, Hirakawa Y, Uchiyama H, Hiraoka N. BK virus pneumonia following stem cell transplantation against diffuse large B-cell lymphoma. Respirol case reports. 2018;6(7): e00348
  7. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. N Engl J Med. 2002;347(7):488-496
  8. Galan A, Rauch CA, Otis CN. Fatal BK polyoma viral pneumonia associated with immunosuppression. Hum Pathol. 2005;36(9):1031-1034
  9. Blazquez-Navarro A, Dang-Heine C, Wittenbrink N, et al. BKV, CMV, and EBV Interactions and their Effect on Graft Function One Year Post-Renal Transplantation: Results from a Large Multi-Centre Study. EBioMedicine. 2018; 34:113-121
  10. Sandler ES, Aquino VM, Goss-Shohet E, Hinrichs S, Krisher K. BK papova virus pneumonia following hematopoietic stem cell transplantation. Bone Marrow Transplant. 1997;20(2):163-165
  11. Toyoda M, Puliyanda DP, Amet N, et al. Co-infection of polyomavirus-BK and cytomegalovirus in renal transplant recipients. Transplantation. 2005;80(2):198-205
  12. Akazawa Y, Terada Y, Yamane T, et al. Fatal BK virus pneumonia following stem cell transplantation. Transpl Infect Dis. 2012;14(6):E142-6
  13. Zaman RA, Ettenger RB, Cheam H, Malekzadeh MH, Tsai EW. A novel treatment regimen for BK viremia. Transplantation. 2014;97(11):1166-1171.