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Dergiler / Medical Science and Discovery / 2016 / Cilt: 3 Sayı: 3

Acute myeloid leukemia under lenalidomide therapy in a patient with multiple myeloma

Ali ESER
Funda PEPEDİL TANRİKULU
Ayse Tulin FİRATLİ TUGLULAR
Sayfa
151–2
Yayın Tarihi
2016-03-15
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Although possible association between SPMs in patients receiving lenalidomide can be attributed to previous melphalan use, potential SPM risk with lenalidomide cannot still be ruled out safely

📌 3 Maddede Bu Makale

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Amaç & Hipotez:A 53-year-old patient who had a 7 year history of multiple myeloma was diagnosed with high risk myelodysplastic syndrome while on lenalidomide treatment.
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Temel Bulgular & Veri:Progression to acute myeloid leukemia has occurred during the following 4 months.
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Sonuç & Katkı:Although possible association between SPMs in patients receiving lenalidomide can be attributed to previous melphalan use, potential SPM risk with lenalidomide cannot still be ruled out safely
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Multiple myeloma · Lenalidomide · Acute myeloid leukemia

Abstract

A 53-year-old patient who had a 7 year history of multiple myeloma was diagnosed with high risk myelodysplastic syndrome while on lenalidomide treatment. Progression to acute myeloid leukemia has occurred during the following 4 months. Like our case, secondary primary malignancies (SPMs) can rarely complicate treatment of multiple myeloma. Although possible association between SPMs in patients receiving lenalidomide can be attributed to previous melphalan use, potential SPM risk with lenalidomide cannot still be ruled out safely

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Bu Makaleye Atıf Yap

ESER, A., TANRİKULU, F. P., TUGLULAR, A. T. F. (2016). Acute myeloid leukemia under lenalidomide therapy in a patient with multiple myeloma. Medical Science and Discovery, Cilt: 3 Sayı: 3, 151–2. https://ajindex.com/articles/1003084

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Kaynakça (6)

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  3. McCarthy PL, Owzar K, Hofmeister CC, Hurd DD, Hassoun H, Richardson PG, et al. Lenalidomide after stem-cell transplantation for multiple myeloma. N Engl J Med. 2012;366(19):1770-81.
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  5. Dimopoulos MA, Richardson PG, Brandenburg N, Yu Z, Weber DM, Niesvizky R, et al. A review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomide. Blood. 2012;119(12):2764-7.
  6. Rossi AC, Mark TM, Jayabalan D, Christos PJ, Zafar F, Pekle K, et al. Incidence of second primary malignancies (SPM) after 6-years follow-up of continuous lenalidomide in first-line treatment of multiple myeloma (MM). J Clin Oncol. 2011;29: abstr 8008.