A CASE OF FACIAL ASYMMETRY Neurofibromatosis type 1 with subcutaneous mass in occipital region, bilateral lisch nodules of iris and cafe- au- lait spots.

Köksal Yuca, Nebi Yılmaz, Adnan Çınal, Ömer Etlik, Muzaffer Kırış

Abstract

Neurofibromatosis type 1 (NF1) has been a well-documented and described disease process since 1882, when it was first described by Friedrich von Recklinghausen (1). NF1 is a multisystem hamartomatous disorder with protean expression of cutaneous, neurologic, skeletal, visceral, and ocular manifestations (2). Children and adolescents with NF1 have a high incidence of CNS anomalies (3). Lisch nodules are a component of NF1 and, when present, are included in the clinical diagnostic criteria for NF1 but as an isolated finding are not considered diagnostic.

Özet

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