An Acute Brucellosis Case Presented with Pancytopenia and Hepatitis

Özet

Brucellosis is a common zoonotic disease in endemic areas like Turkey. It is an infection that can bemanifested by extensive clinical findings, for this reason it can be difficult to diagnose. In humans,treatment of the disease requires long-lasting combined antibiotics and appropriate treatmentregimens, but it is often difficult to achieve this success in countries with limited resources.Therefore, this may be an important economic burden in terms of both cost of treatment andpotential loss of labor in individuals affected by brucellosis. A 23-year-old male patient who waspresented with fever, pancytopenia and hepatitis, was hospitalized with the aim of investigating theetiology of fever. On laboratory findings supporting the Brusella disease, we started treatment withthe combination of gentamycin and doxycycline to avoid drug-induced hepatotoxic effect. Laboratoryfindings were successfully improved while clinical complaints decreased. Brucella disease should bekept in mind in in endemic areas, concerning patients with abnormal laboratory findings of thehematopoietic or hepatobiliary system. Taking into consideration the side effects of the medicinesused in the treatment of the disease, effective and least toxic combinations should be selected.