Journals / Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji / 2019 / Cilt: 8 Sayı: 2

PHENOLIC COMPOUNDS DETERMINATION AND ANTIOXIDANT ACTIVITY OF TEUCRIUM CAVERNARUM

Pages
229–237
DOI
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Özet

ABSTRACT The current study was aimed to determine phenolic compounds profile and antioxidant activity of 70% MeOH extract of Teucrium cavernarum P.H. Davis which is an endemic plant of Turkey. According to LC-MS/MS analysis of the extract, forsythoside A, forsythoside B, luteolin-7-gucoside, cirsimaritin and cirsiliol were determined as the major compounds. The total phenolic and radical scavenging activities of the extract were also determined. According to antioxidant activity results, IC50 value of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect was determined as 0.12 ±0.01 mg/mL. 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging activity was also determined as 1.2 mM trolox equivalent (TEAC).

Keywords: Teucrium cavernarum, Antioxidant activity, LC-MS/MS, Phenolic