Journals / Journal of Immunology and Clinical Microbiology / 2022 / Cilt: 7 - Sayı: 3
Evaluation of HBsAg, Anti-HCV and Anti-HIV Reactivity in Covid-19 Patients
- Pages
- 51–57
- DOI
- —
Abstract
Objective:MethodsMethods2 emerged in China’s Wuhan province in 2019 and spread allover the world in a short period of time. It is a positive-sense, enveloped RNA virus that belong to the Coronaviridae family and is the causative agent of Covid-19 disease. It primarily represents with pulmonary manifestations, but it can affect many systems, especially the liver. Measures taken to educethe impact of the pandemic caused disruptions in the follow-up and treatment of chronic diseases such as hepatitis. In this study, HBsAg, Anti-HCV and Anti-HIV parameters and mortality rates of patients with confirmed Covid-19 diagnosis admitted to our hospital and followed up in out patient clinics, services and intensive care units were investigated.Methods: HBsAg, Anti-HCV and Anti-HIV data of patients whose diagnoses were confirmed by SARS-CoV-2 PCR test were obtained retrospectively from the hospitalin formation system.Results: There were 749 patients included in the study, 352 (47%) male and 397 (53%) female. The patients were divided into two groups according to survival. The meanage of the mortal group (n=144) was found to be higher than the survivor group (n=605) with a statistically significant difference (p<0.001). When the mortality rates in the patient groups with reactive HBsAg and Anti-HCV results were examined, no statistically significan tdifference was found (p=0.59, p=0.13, respectively). The patients were divided into three sub groups according to the units theywerefollowed, as outpatientclinic (n=265), services (n=357) andintensivecareunit (n=127). The mortality rate of the patients followed in the intensive care unit was higher andstatistically significant (p<0.001).Conclusion: We think that, in addition to the primary effects of the pandemic on public health, it also has negative effects on the follow-up and treatment of chronic diseases and it is necessary to contribute to theliterature by conductings tudies on this subject.Objective
Özet
Amaç: Çin’in Wuhan eyaletinde 2019 yılında ortaya çıkıp kısa sürede tüm dünyaya yayılan SARS-CoV-2; Coronaviridae ailesine ait pozitif polariteli, zarflı bir RNA virüsü olup Covid-19 hastalığının etkenidir. Primer olarak akciğer tutulumu ile seyreden bu hastalığın karaciğer başta olmak üzere pek çok sistemi tutabildiği gösterilmiştir. Pandeminin etkisini azaltmak için alınan önlemler hepatit gibi kronik hastalıkların takip ve tedavisinde aksamalara sebep olmuştur. Bu çalışmada hastanemize başvuran ve Covid-19 tanısı doğrulanmış poliklinik, servis ve yoğun bakım birimlerinde takipli hastaların HBsAg, Anti-HCV ve Anti-HIV parametreleri ile mortalite oranları incelenmiştir.