Mismatch negativity and schizophrenia

Abstract

Mismatch Negativity is produced by our brain's automatic response to a random change in the presented auditory stimulus that exceeds a certain limit and corresponds to a noticeable behavioral discrimination threshold. Mismatch Negativity, which emerged thanks to the oddball paradigm, is acquered in the functions of the brain that do not require attention. Although it is preferred in many areas in terms of clinical use, its most common use for schizophrenia. The aim of this review is to have information about possible Mismatch Negativity findings in schizophrenia by recognizing the Mismatch Negativity test and schizophrenia, which is closely related to public health.

Özet

c response to a random change in the presented auditory stimulus that exceeds a certain limit and corresponds to a noticeable behavioral discrimination threshold. Mismatch Negativity, which emerged thanks to the oddball paradigm, is acquered in the functions of the brain that do not require attention. Although it is preferred in many areas in terms of clinical use, its most common use for schizophrenia. The aim of this review is to have information about possible Mismatch Negativity findings in schizophrenia by recognizing the Mismatch Negativity test and schizophrenia, which is closely related to public health. Mismatch negativity (uyumsuzluk negatifliği) beynimizin, sunulan işitsel uyaranda belli bir sınırı aşan ve fark edilebilir davranışsal ayırt etme eşiğine karşılık gelen random bir değişikliğe otomatik cevap oluşturması ile üretilir. Oddball paradigması sonucu meydana gelen mismatch negativity beynin dikkate ihtiyaç duymayan faaliyetlerinde elde edilmektedir. Klinik kullanımı açısından birçok alanda tercih edilmekle beraber en yaygın kullanımı şizofreni seyrinde olmaktadır. Bu derleme de amaç mismatch negativity testini ve toplum sağlığını yakından ilgilendiren şizofreniyi tanıyarak şizofrenide olası Mismatch Negativity bulguları hakkında bilgi sahibi olmaktır.