Journals / Türk Kadın Sağlığı ve Neonatoloji Dergisi / 2021 / Cilt: 3 - Sayı: 1
Comparison of clinicopathological and survival analysis of uterus confined carcinosarcoma and grade 3 endometrioid endometrium cancer
- Pages
- 7–11
- DOI
- —
Abstract
Aim: Although Grade 3 endometrioid endometrial cancer (G3ECC) and carcinosarcomas (CS) are included in the same risk group among endometrial cancer cases in the consensus published by ESMO-ESGO-ESRTO in 2015, the biological behaviors of these histological types are different. In this study, we aimed to compare grade 3 endometrioid endometrial cancer cases with carcinosarcoma cases limited to the uterus in terms of clinical results and survival analysis.Material and Methods: Grade 3 endometrioid endometrial cancer (G3 ECC) cases (n = 67) in which the disease is limited to the uterus and uterine limited CS cases (n = 54) were compared in terms of clinical results and survival analysis.Results: Despite the limited disease in the uterus, survival was significantly worse in patients with carcinosarcoma. While recurrence was 10.5% in G3ECC, this rate was found as 27.8% in CS (p = 0.011).Conclusion: Carcinosarcomas may have a worse prognosis than G3 endometrioid endometrial cancers even in the early stages.
Özet
Amaç: Grade 3 endometrioid endometrium kanseri (G3ECC) ve karsinosarkom (KS), ESMO-ESGO-ESRTO’un 2015’de yayınladığı konsensüsunda endometrium kanseri olguları içinde aynı risk grubunda yer alsa da, bu histolojik tiplerin biyolojik davranışları farklıdır. Bu çalışmada G3ECC olguları ile uterusa sınırlı KS vakalarının klinik sonuçlar ve sağkalım analizleri açısından karşılaştırılması amaçlandı.