Determination of bisphenol A in plastic bottle packaging beverage samples using ultrasonic-assisted extraction and flame atomic absorption spectrometry

Abstract

In this work, a versatile and simple ultrasound-assisted extraction (UAE) procedure, which provides high separation efficiency for bisphenol A, was developed for its indirect determination in beverages in contact with plastic containers by flame atomic absorption spectrometry (FAAS). The method is based on charge transfer reaction, in which bisphenol A reacts with Cu(II) in alkaline tartrate solutions of pH 8.0 to produce Cu(I), which reacts with ion-pairing reagent, promethazine being a phenothiazine derivative (PMZ), in presence of cetyltrimethylammonium bromide (CTAB). For the indirect determination of bisphenol A using FAAS, the signal change of Cu(II) was investigated in detail depending on bisphenol A concentration. At optimal conditions, the analytical features of the method were obtained as follows; linear ranges of 1.5-100 µg L-1 for direct aqueous calibration solutions and 3-125 µg L-1 for matrix matched calibration solutions;the limits of detection and quantification of 0.47 and 1.56 µg L-1; sensitivity enhancement and preconcentration factors of 135 and 150, respectively. The validity of method was tested by repeatability/reproducibility precision studies using standard addition method. As the last, the method was successfully applied to determination of bisphenol A in selected samples.