The importance of mean platelet volume to lymphocyte ratio in predicting atrial fibrillation after coronary bypass operations

Abstract

Background/Aim: The rate of postoperative atrial fibrillation (PoAF) after coronary artery bypass graft (CABG) operations ranges between 25-40%. Inflammation plays an important role in the pathogenesis of PoAF, and mean platelet volume and lymphocyte count are important inflammatory parameters. This study aimed to investigate the importance of the mean platelet to lymphocyte ratio (MPVLR) in predicting PoAF after CABG operations. Methods: Three hundred and eighty consecutive patients who underwent on-pump CABG in our clinic between August 2016 and August 2020 were included in this retrospective observational cohort study. Patients with a known history of atrial fibrillation, reoperations, emergency operations, patients who had acute coronary syndrome within the last month, combined surgeries, those with systemic inflammatory disease, chronic autoimmune disease, chronic liver/kidney disease, and hematological diseases, and patients under steroid therapy were excluded from the study. Patients who did not develop postoperative PoAF were included in Group 1, while those who did were included in Group 2. Results: There were 319 patients in Group 1 with a median age of 59 (32-83) years, and 61 patients in Group 2, with a median age of 66 (38-86) years (P