COVID-19 and myocarditis/myocardial injury

Abstract

Myocarditis is defined as inflammation of the myocardium, and it presents with different clinical pictures, and its diagnosis has some difficulties. The prognosis of myocarditis is aetiology-dependent, and treatment is fundemantally supportive except for “endometrial biopsy proven” cases which requires spesific therapies including immunomodulators and intravenous immunoglobulins. SARS-CoV-2 affects cardiovascular systems directly or via indirectly mechanisms. COVID-19 infection increases the risks of myocardial injury, myocarditis, myocardial infarction, heart failure, venous thromboembolism and arrhythmias. The underlying mechanism of troponin elevation during COVID-19 infections is not exactly explained. In this review, the relationship between COVID-19 and myocardial involvement was discussed. Still, multidisciplinary trials are needed to explain this important situation.