The predictive value of systemic immune inflammation index on long-term outcomes among acute pulmonary embolism patients

Abstract

Aim: Systemic immune-inflammation index (SII) is a novel marker that predicts adverse clinical outcomes among patients with malignancy and cardiovascular diseases. In the present study, we hypothesized that SII could provide more additional information in the prediction of long-term mortality among patients with acute pulmonary embolism (APE). Methods: Consecutive patients (n=514) who were followed up and treated with a diagnosis of APE were included in the study. The study group was divided into those survivors and non-survivors. Demographic, clinical, laboratory, and echocardiographic characteristics were compared between groups. Results: A total of 28 (5.4%) patients died in the 30 days. Besides, during a follow-up period of 29 [12-53] months, 52 patients (10.1%) died. In the Cox-regression analysis, age [odds ratio (OR): 1.052, 95% confidence interval (CI): 1.034–1.071; p