Association Between ABO Blood Group With Parkinson’s Disease

Abstract

AbstractBackground/Aims:Parkinson's disease is a common neurodegenerative disease that seen in adulthood. Most prevelant symptoms are resting tremor, rigidity, bradykinesia ,gait disturbance, and postural abnormalities.Disorders related with ABO blood group are infectious disease(cholera,helicobacter pylori,echerichia coli),cardiovascular disease,malignancies and allergic status.We objectived to elucidate the association between ABO blood group and Parkinson's disease Materials -Methods: We investigated retrospectively the files of 264 adult patients who were diagnosed with Parkinson's disease and had blood type between January 2008 and December 2018 in neurology outpatient clinics included in the study Results: Distribution of blood groups in patients as follows : ARh(+): 94(%35,6), ARh(-):15(%5,7),BRh(+):44(%16,7),BRh(-):8(%3), ABRh(+):18(%6,8), ABRh(-):4(%1,5),0Rh(+):71(%26,9),0Rh(-):10(%3,8) Conclusions: When we consider the pathogenesis of Parkinson’s Disease , we think of the antigenic structure of blood groups may be effective in this process.