Journals / İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi / 2020 / Cilt: 5 - Sayı: 2
Effect of COVID-19 on Musculoskeletal System
- Pages
- 179–182
- DOI
- —
Abstract
COVID-19 disease caused by the SARS-CoV-2 virus adversely affects the musculoskeletal system. Pathological changes in the musculoskeletal system occur due to the direct viral exposure of muscle tissue, synovium and cortical bone cells via the transmembrane protease, serine 2 and angiotensin converting enzyme 2 (ACE2) receptor, or due to cytokines and proinflammatory molecules. In addition, corticosteroids used in the treatment of the disease increase the disruption in the musculoskeletal system. Severe myalgia and arthralgia, high creatine kinase level and decreased bone density are the main symptoms. Highly genetic and pathological similarities between SARS-CoV-1 – SARS-CoV-2 enable short and long-term musculoskeletal complications to be predicted for patients with severe COVID-19 disease. Aerobic and strengthening exercises can be used efficiently against the disruption of the musculoskeletal system caused by COVID-19.
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