Journals / Eastern Anatolian Journal of Science / 2018 / Cilt: 4 - Sayı: 2
Toxic Effect of Pesticides on Aldose Reductase Enzyme.
- Pages
- 1–5
- DOI
- —
Abstract
In this study, the effect of pesticides on the enzyme activity of Aldose reductase (AR) (EC 1.1.1.21), which is involved in polyol pathway and detoxification reactions, has been investigated.For this purpose, AR enzyme was purified from chicken liver and the IC50 values were plotted as % Activity-[I] for pesticides with inhibition effect and The maximum inhibitory effect was determined at 2,4,5-T with 162μM.