Effects of Tribulus terrestris, Avena sativa and White Ginseng on Adiponectin, Leptin, Resistin, Fatty Acid Binding Protein 4, Homocysteine and Paraoxonase-1 Levels in Hypercholesterolemic Rats

Abstract

This study was aimed to evaluate the effects of Tribulus terrestris (TT), Avena sativa (AS), white ginseng (WG), and a triple combination (TC) powder on adipokines, homocysteine and paraoxonase-1 levels in hypercholesterolemic rats. Hypercholesterolemia in rats was induced by diet added 2% cholesterol. Herbal treatment groups consisted of Group III (TT), Group IV (AS), Group V (WG) and Group VI (triple combination of TT, AS, and WG). Significant increase in total cholesterol, LDL-C, homocysteine, leptin and resistin levels (P0.05) were found in hypercholesterolemic rats. The treatment combination with TT, AS and WG significantly reduced total cholesterol, LDL-C, homocysteine, leptin and resistin levels in hypercholesterolemic rats (P