Determination of AdipoR1 and AdipoR2 receptors gene expression metabolic syndrome occurs with fructose in the diet in rats

Abstract

In this study, it was aimed to investigate serum adiponectin levels and AdipoR1 and AdipoR2 gene expressions in rats with metabolic syndrome with fructose diet. Twenty-eight male Sprague Dawley rats were used for this purpose. The rats in the control group were fed only with water and rat food while the rats in the experimental group were fed with water containing 20% D-fructose and rat food for 16 weeks with ad libitum. In the control and metabolic syndrome groups, weight differences between the beginning and end of the experiment and the abdominal circumference measured at the end of the experiment were found statistically significant at the level of p