Journals / Turkish Journal of Medical Sciences / 2007 / Cilt: 37 - Sayı: 3

A Rare Side Effect of Metformin: Metformin-Induced Hepatotoxicity

Pages
173–175
DOI
—

Abstract

Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.

Özet

Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.

Keywords: Metformin, metformin-associated lactic acidosis, hepatotoxicity, side effect