Journals / Turkish Journal of Chemistry / 1999 / Cilt: 23 - Sayı: 2
Transition Metal Compound Mediated Reduction of a-Amino Acids to 1,2-Amino Alcohols with NaBH4 in Water
- Journal
- Turkish Journal of Chemistry
- Pages
- 123–126
- DOI
- —
Abstract
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.
Özet
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.