Journals / Cumhuriyet Science Journal / 2015 / Cilt: 36 - Sayı: 3
Mutagenic and Anti-mutagenic properties of the essential oil of Jurinea leptoloba DC by Ames Test
- Journal
- Cumhuriyet Science Journal
- Pages
- 1682–1687
- DOI
- —
Abstract
Abstract. The aim of this study was to determine the mutagenic and anti-mutagenic properties of the essential oil of Jurinea leptoloba DC in vitro. The mutagenic and anti-mutagenic activities of the oil was evaluated using the Salmonella typhimurium tester strains TA98 and TA100, together with nitrofluorene for TA98 and sodium azide for TA100 without (-S9) metabolic activation, and 2-aminoantracene for TA98 and TA100 with metabolic (+S9) activation. The results obtained with S. typhimurium suggest that the oil of J. leptoloba can not be exploited as an anti-mutagenic agent with low adverse side effects.