Effect of lidocaine on spinal cord lipid peroxide levels after acute spinal cord trauma in rats

Abstract

A standard spinal cord trauma was performed on control and lidocaine-treated (5 mg/kg. i.p.) rats. Spinal cord lipid peroxide levels in the lidocaine-trcaled group were significantly lower than those of controls. No significant difference was observed in plasma lipid peroxide levels. Our results suggest a protective role of lidocaine against lipid peroxidation after experimental spinal cord trauma in rats.