SavedAdd your journal

Journals / Marmara Medical Journal / 1993 / Cilt: 6 - Sayı: 4

Phosphorylation of elf-2(3 and ef-1 by two ribosoflial kinase fractions

B.kan KAN, İ.m. LONDON, D.h. LEVİN

Pages
140–142
DOI
—

Abstract

Two ribosomal kinase fractions have been partially purified from reticulocyte lysates by DEAE-cellulose and phosphocellulose column chromatography. These fractions autophosphorylated the majority of the bands and phosphorylated EF-1 and elF-2|3. Addition of GSSG (oxidized glutathione) produced a general decrease in phosphorylation. However, phosphorylation of elF-2|3 was enhanced in the presence of GSSG.