Synthesis and Antioxidant Activities of Novel Naphthalimide Derivatives

Abstract

In this study, synthesis and characterization of naphthalimide derivatives containing both amide and urea groups were performed and their antioxidant activities were determined. 4-R-1 8-naphthalic anhydride (R = -H, -NO2 or –NH2) with different functional groups has been chosen as the precursor and reacted with 5,6-diamino-1H-benzo[d]imidazol-2(3H)-one to synthesize the targeted naphthalimide derivatives. ESI-MS and 1H-NMR techniques have been used to characterize the molecules. Antioxidant activities of compounds have been determined by DPPH and peroxide radical scavenging methods.