Therapeutic Benefit of Intracavitary-interstitial Brachytherapy in Cervical Cancer Patients with Small and Large High-risk Clinical Target Volume

Abstract

OBJECTIVE We aimed to investigate the added value of interstitial brachytherapy (IS-BT) over classical intracavitary BT (IC-BT) in terms of target coverage and organ at risk (OAR) sparing among patients for whom an optimal dose distribution could not be provided without IS-ICBT and also to determine if the magnitude advantage provided by IS-BT is similar in patients smaller (