ABO Kan Grupları Diyabetik Nefropati ile İlişkilidir

Semih YILMAZ, Ferhan ELMALI, Bülent ESER, Bülent TOKGÖZ, Oktay OYMAK, Murat Hayri SİPAHİOĞLU, İsmail KOÇYİĞİT, Aydın ÜNAL

Abstract

OBJECTIVE: In this study, we aimed to evaluate any possible relationship between DN and ABO-Rh blood groups.MATERIAL and METHODS: The study included 743 patients with DN and 25253 healthy donors that presented at the Erciyes University Blood Bank in the year 2012. RESULTS: There was a significant difference between patients with DN and the control group in terms of distribution of ABO blood groups and Rh factor (p: 0.002). A Rh positive blood group was remarkably frequent in patients with DN compared to control subjects (43.3% vs. 38.5%, respectively) whereas frequency of the O Rh positive blood group was remarkably lower in patients with DN compared to control subjects (26.1% vs. 29.5%, respectively). There was a significant difference between patients with DN and the control group in terms of the distribution of the ABO blood groups (p: 0.001). The A blood group was remarkably frequent in patients with DN compared to control subjects (48.3% vs. 43.6%, respectively) whereas frequency of the O blood group was remarkably lower in patients with DN compared to control subjects (28.5% vs. 34.1%, respectively)

Özet

amaç: Bu çalışmada, diyabetik nefropati (DN) ve ABO-Rh kan grupları arasında olası herhangi bir ilişkiyi değerlendirmeyi amaçladık. GEREÇ ve YÖNTEMLER: Bu çalışmaya 743 DN'li hasta ile 2012 yılında Erciyes Üniversitesi Kan Bankası'na bağışta bulunan 25253 sağlıklı donör dahil edildi