Journals / Turkish Journal of Surgery / 2019 / Cilt: 35 - Sayı: 1
Malignancy risk for thyroid nodules larger than 4 cm and diagnostic reliability of ultrasound-guided FNAB results
- Journal
- Turkish Journal of Surgery
- Pages
- 13–18
- DOI
- —
Abstract
Objective: Our aim in the present study was to investigate the relation between thyroid nodule diameter and malignancy, and the diagnostic accuracy of fine needle aspiration biopsy (FNAB) for thyroid nodules larger than 4 cm. Material and Methods: Preoperative patient demographics such as age and gender, thyroid nodule diameter, FNAB results and postoperative pathology results were recorded. The relation between age, gender, thyroid nodule size of the patients and malignancy was examined. Also, the sensitivity, specificity, false negativity, false positivity and accuracy rates of FNBA of the patients whose thyroid nodule size was lower than 4 cm and the ones whose thyroid nodule size was higher than 4 cm were analyzed. Results: There was no significant difference between males and females in terms of malignancy rate (p= 0.15). There was no significant relation between malignancy and patient age (p= 0.92). No significant difference was found between the group with thyroid nodule diameter of > 4 cm and the group thyroid with nodule diameter of 4 cm, sensitivity, specificity, false negativity, false positivity, and accuracy rates of FNAB were 15%, 100%, 84%, 0%, and 70%, respectively. In the group with thyroid nodule diameter of 4 cm diameter were compared to the thyroid nodules with < 4 cm diameter.
Özet
Giriş ve Amaç: Bu çalışmadaki amacımız tiroid nodül çapı ile malignite arasındaki ilişkiye ve 4 cm‘ den büyük tiroid nodüllerinde ince iğne aspirasyon biyopsisi (İİAB)’nin tanısal doğruluğunu araştırmak idi. Gereç ve Yöntem: Hastaların ameliyat öncesi yaş, cinsiyet gibi demografik özellikleri, tiroid nodül çapları, İİAB sonuçları ve ameliyat sonrası patoloji sonuçları kaydedildi. Yaş, cinsiyet ve tiroid nodül çapı ile malignite arasındaki ilişki araştırıldı. Ayrıca tiroid nodül çapı > 4 cm ve 4 cm olan grup ile tiroid nodül çapı 4 cm olan grupta İİAB’nin sensivite, spesifite, yanlış negatiflik, yanlış pozitiflik ve doğruluk oranları sırasıyla %15, %100, %84, %0 ve %70 idi. Tiroid nodül çapı 4 cm tiroid nodüllerinde < 4 cm nodüllerle kıyaslandığında İİAB’nin duyarlılığının daha düşük ve yanlış negatiflik oranının daha yüksek olduğu bulundu.