Novel Straight-Chained Sulfanyl Members of Arylamino-1,4- naphthoquinones: Synthesis and Characterization

Abstract

The aim of this paper is to describe the synthesis and characterization of new members of straight-chained sulfanyl derivatives of arylamino-1,4-naphthoquinones. 2-(4(trifluoromethyl)phenylamino)-3-chloronaphthalene-1,4-dione (trifluoromethyl)phenylamino)-3-chloronaphthalene-1,4-dione nucleophilic substitution reaction between 2,3-dichloronaphthalene-1,4-dione' (1) and arylamines containing a trifluoro group at the meta or para positions (2a, 2b) were used as building blocks for straight-chained sulfanyl arylamino-1,4-naphthoquinones. The structures of all the novel compounds (5a-f) were established by spectroscopic evidence including FTIR, 1H NMR, 13C NMR, and MS data