Association of monocyte to high-density lipoprotein ratio with bare-metal stent restenosis in STEMI patients treated with primary PCI

Abstract

OBJECTIVE: Monocyte to high-density lipoprotein ratio (MHR) has recently been postulated as a novel parameter relatedto adverse cardiovascular outcomes. In this study, we aimed to investigate the correlation of MHR with stent restenosis (SR)rates after the primary percutaneous coronary intervention (PCI) and bare-metal stent (BMS) implantation.METHODS: In this study, patients who had undergone primary PCI for STEMI and had a control angiogram during follow-upwere retrospectively recruited. Patients were categorized according to admission MHR tertiles, clinical and angiographic datawere compared. In addition, predictors of SR were evaluated with logistic regression analysis.RESULTS: A total number of 448 patients (240 patients with SR and 208 patients without SR) were included in this study.Patients were categorized into three groups according to tertiles of admission MHR. During a follow-up period of median 12months, the rate of SR was significantly higher in patients with higher MHR levels (45% in tertile 1, 54% in tertile 2 and 62%in tertile 3, p