How to Set Up a Molecular Pathology Lab: A Guide for Pathologists

Abstract

In today’s pathology practice, pathologists combine molecular tests with conventional histopathological methods. Pathology laboratoriesshould therefore be designed and operated in accordance with the requirements of molecular testing procedures. While the specifics of therequirements may vary depending on the spectrum of the tests that will be performed, there are several basic criteria that need to be fulfilledfor standardization. Adequate space, appropriate equipment and qualified personnel are required to establish a molecular pathology laboratory.One of the most important points that should be taken into consideration while designing a molecular pathology laboratory is to create a plan toprevent contamination. As molecular diagnosis has a major role in treatment decisions, the management of the molecular pathology laboratoryis of utmost importance. In this review, the criteria required to establish an optimal molecular pathology laboratory will be reviewed.