Evaluation of serum 25-hydroxy vitamin d levels in premenapousal psoriasis patients

Abstract

Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients andcompare it with the same age and sex matched healthy volunteers.Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were included in the study. Serum 25-hydroxyvitamin D levels were compared between the two groups; also the relationship of disease activity and 25-hydroxy Vitamin D levels wereexamined in patients with psoriasis. Probability values of 0.05). In addition, the mean 25-hydroxyvitamin D levels were not signifcantly different among the two groups (p>0.05). 25-hydroxy vitamin D levels were no signifcantly different inpatients with and without psoriatic arthritis (p>0.05). No signifcant correlation was found between psoriasis area severity index PASI values,age or 25-hydroxy vitamin D levels (p>0.05).Conclusion: The low levels of vitamin D in population is reported to be common. In our study, similar low vitamin D levels were foundin healthy volunteers and premenopausal psoriasis patients. Serum 25-hydroxy vitamin D levels were not correlated with disease activityin patients with psoriasis. Correlation between psoriasis, disease activity and vitamin D levels should be investigated in larger populations.