Prognostic Importance of Ki-67 Labeling Index in Grade II Glial Tumors

Meryem AKTAN, Gül KANYILMAZ, Eray KARAHACIOĞLU, Hatice ÖNDER, Hüseyin BORA, Mehmet KOÇ, Haldun Şükrü ERKAL, Eda YİRMİBEŞOĞLU ERKAL

Abstract

OBJECTIVETo date, several methods have been identified for predicting the prognostic subgroups of grade II gliomas; however, these methods have some limitations in predicting survival. So, we aimed to determinethe predictive role of Ki-67 labeling index (LI) on survival.METHODSBetween 1995 and 2014, patients with grade II gliomas were retrospectively analyzed. All patients received radiotherapy (RT).RESULTSThis study included 78 patients with median 44 (range, 6–137) months follow-up. Patients aged ≥40 yearshad a poorer overall survival (OS) than those aged