Organ Sparing Approach in Bilateral Testis Tumors: A Short Review of the Literature with a Featuring Case

Abstract

Dear Editor, Testicular cancer (TC) is very rare in clinical practice. It represents only 1-2% of all cancers.[1] However, TC is the most common malignancy in men between 15 and 40 years old.[2] Race, cryptorchidism, genetics, maternal estrogen exposure, and previous TC are main known risk factors.[3,4] Western and Northern Europe populations have significantly high incidence for TC.[5] Pathological classification of TCs consists of germ cell tumors (GCT), stromal tumors, ITGCN, and others. More than 90% of TC has GCT histology.[6] GCT is divided into 2 main subgroups such as seminomas and non-seminomatous tumors. Non-seminomatous GCT has 5 subtypes such as embryonal carcinoma, yolk sac tumors, choriocarcinoma, teratoma, and mixed tumors. Our patient has mixed GCT histology. Average age of presentation of mixed GCT is 30 years old.[7] Any combination of histological subtypes is formally possible, although admixture of embryonal carcinoma and teratoma is more frequent.[8]