Thymol May be an Effective Agent in the Treatment of Liver and Kidney Damages Caused by Ionizing Radiation

Hilal KIZILTUNÇ ÖZMEN, Yılmaz ŞAHİN, Ayhan TANYELİ, Fazile Nur EKİNCİ AKDEMİR, Gizem ESER, Serkan YILDIRIM, Yasin BAYIR, Ayşenur KAHRAMANLAR

Abstract

OBJECTIVE The goal of the present study was to evaluate the therapeutic efficacy of thymol in diminishing the damages to the liver and kidney tissues caused by the application of ionizing radiation. METHODS The experimental rats were randomized and grouped as follows: Group I (control), Group II (receiving ionizing radiation), and Group III (receiving thymol + ionizing radiation). Pathological tissue damage was assessed by immunohistochemical and biochemical analyses using chemical methods. RESULTS The level of plasma malondialdehyde (MDA) in both the tissues were significantly elevated in Group II compared to that in Group I (p